Anthemintic drugs. Their ovicidal and larvicidal actions was written by Goulart, Enio G.;De Arruda, Mercia E.;Jourdan, Myriam C.. And the article was included in Revista Brasileira de Medicina in 1974.Quality Control of Piperazine Dihydrochloride This article mentions the following:
Of 9 chemotherapeutic anthelmintics tested in vitro against eggs and larvae of Ascaris lumbricoides, Trichuris trichiura, and Ancylostoma caninum, pyrantel pamoate [22204-24-6] and tetrachloroethylene [127-18-4] (10 and 100 mg each) inhibited development of A. caninum; similar results were obtained with 1 mg tetramisole-HCl (I-HCl) [5086-74-8] and thiabendazole (II) [148-79-8]. Stilbazium iodide [3784-99-4], pyrvinium pamoate [3546-41-6], and bephenium hydroxynaphthoate [3818-50-6] showed anthelmintic activity which was directly related to the concentrations None of the compounds tested showed embryogenic blocking activity against A. lumbricoides or T. trichiura. Prophylactic treatments of contaminated soil or organic fertilizer are apparently ineffective. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Quality Control of Piperazine Dihydrochloride).
Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine is a fairly basic compound and is an amine solvent. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Quality Control of Piperazine Dihydrochloride
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics