Category: piperidines

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Name: 2,2,6,6-Tetramethyl-4-piperidinol.

Membrat, Romain;Vasseur, Alexandre;Giordano, Laurent;Martinez, Alexandre;Nuel, Didier research published 《 General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation》, the research content is summarized as follows. A convenient method to access a broad variety of N-alkyl-(2,2,6,6)-tetramethylpiperidin-4-ol compounds is reported. The thermal treatment of a mixture of (2,2,6,6)-tetramethylpiperidin-4-ol and allyl or benzyl bromide derivatives gave the corresponding N-alkylated compounds in good yields while leaving the hydroxyl functional group intact. Whereas 40h were needed to reach complete conversion, microwave irradiation allowed the reaction time to be reduced (20 min) and improved the yields in most cases.

Name: 2,2,6,6-Tetramethyl-4-piperidinol, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Category: piperidines.

Meng, Fanyue;Yu, Lei;Song, Bing;Zhao, Yan;Zhi, Zejian;Lin, Chenbin;Song, Min research published 《 Insights into the mechanism of redox pairs and oxygen vacancies of Fe₂O₃@CoFe₂O₄ hybrids for effcient refractory organic pollutants degradation》, the research content is summarized as follows. The core-shell Fe2O3@CoFe2O4 hybrids microspheres with abundant oxygen vacancies were synthesized through in-situ ion exchange-calcination method and employed to induce peroxymonosulfate (PMS) to eliminate organic pollutants. The superior catalytic activity and stability of Fe2O3@CoFe2O4 were attributed to the synergistic effects of M2+/M3+ (M denotes Co or Fe) redox cycles. SO·-4, ·OH, O·-2 and 1O2 were proved to be the main reactive oxygen species (ROS) involved in the phenol degradation process through quenching experiments and EPR measurements, while the surface-bound SO·-4 played a dominant role. Trace metal ions leached during the reaction enhanced the PMS activation, and the oxygen vacancies electron transfer process played a critical role in the formation of O·-2/1O2 and the cycle of M2+/M3+ redox pairs. The formation of ROS and function of 1O2 were also revealed from bulk reaction and interface reaction. This study highlighted the simultaneous evolution of PMS reduction and oxidation to generate ROS, which provided an insight into the efficient catalytic degradation of persistent organic pollutants (POPs).

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Category: piperidines

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. SDS of cas: 84358-13-4.

Merkens, Kay;Aguilar Troyano, Francisco Jose;Djossou, Jonas;Gomez-Suarez, Adrian research published 《 Synthesis of unnatural α-amino acid derivatives via light-mediated radical decarboxylative processes》, the research content is summarized as follows. Unnatural amino acids (UAAs) are key building blocks with widespread application across several scientific fields. Therefore, it is highly attractive to develop straightforward and simple methodologies capable of granting quick access to these species. Herein we report a light-mediated protocol for the synthesis of UAA via radical decarboxylative processes. This methodol., which employs readily available and abundant starting materials – such as carboxylic and α-keto acids – proceeds under very mild reaction conditions and shows a high functional group tolerance. In addition, the products of the radical reaction can be readily derivatized to grant rapid access to complex UAAs.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., SDS of cas: 84358-13-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. This gave the compound its name. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Other examples are the fire ant toxin solenopsin, the nicotine analog anabasine of tree tobacco (Nicotiana glauca), lobeline of Indian tobacco. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Mi, Xueyue;Zhong, Hui;Zhang, Hongxiang;Xu, Shizhe;Li, Yi;Wang, Haitao;Zhan, Sihui;Crittenden, John C. research published 《 Facilitating Redox Cycles of Copper Species by Pollutants in Peroxymonosulfate Activation》, the research content is summarized as follows. The redox behavior of metal active sites determines the rate of heterogeneous catalysis in peroxymonosulfate activation. Previous reports focused on the construction of catalysts for accelerating interfacial electron transfer. In this work, a new strategy was proposed for facilitating valence cycles of Cu⁺/Cu²⁺ by using pollutants. The 2.5Cu/CeO₂/PMS system was capable of achieving the efficient removal of pollutants, including tetracycline, oxytetracycline, and rhodamine B, in a wide pH working range. In the presence of tetracycline, a Cu-N bond was formed between the -NH₂ group of tetracycline and the Cu site of the catalyst, showing that the coordination of Cu active sites changed to CuO₄N₁. The charge of CuO₄N₁ active sites rearranged, making it easier to obtain electrons and promote the PMS oxidation, thereby accelerating the reduction of Cu²⁺ to Cu⁺ and PMS activation. The PMS activation system showed excellent sustainability and selectivity for the removal of organic pollutants. This study provides a novel routine to promote peroxymonosulfate activation by utilizing pollutants to accelerate the redox behavior of metal species.

2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. It is a colorless liquid with an odor described as objectionable, and typical of amines. Quality Control of 2403-88-5.

Li, Xiang;Zhang, Jiajia;Qin, Yang;Zhang, Xingli;Zou, Wei;Ding, Linjie;Zhou, Minghua research published 《 Enhanced removal of organic contaminants by novel iron-carbon and premagnetization: Performance and enhancement mechanism》, the research content is summarized as follows. Iron-carbon (Fe-C) microelectrolysis has attracted considerable attention in wastewater treatment due to its excellent ability to remove contaminants. Herein, novel Fe-C granules were synthesized by simple calcination method for removing organic contaminations, and a cost-effective and environmentally friendly method, namely pre-magnetization, was used to improve the micro-electrolysis performance of Fe-C. Batch experiments proved that premagnetized iron-carbon (pre-Fe-C) could significantly improve the removal of methyl orange (MO) at different Fe-C mass ratios (1:2-2:1), material dosages (1.0-2.5 g/L), initial pH values (3.0-5.0), and MO concentrations (10.0-50.0 mg/L). Electrochem. anal. showed that premagnetization could increase the c.d. and reduce the charge transfer resistance of the microelectrolysis system, making Fe-C more susceptible to electrochem. corrosion. Characterizations confirmed that the corrosion products of the materials included FeO, Fe₂O3, and Fe₃O₄, and more corrosion products were formed in the pre-Fe-C system. Radical quenching experiments and ESR spectroscopy verified that •OH, ¹O₂, and O₂^-• were all involved in pollutant removal, and premagnetization could promote the generation of more reactive oxygen species. Overall, the pre-Fe-C process could effectively remove various organic pollutants, exhibit good adaptability to complex water environments, and hold potential for industrial applications.

Quality Control of 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol.

Li, Xiaoying;Yu, Zhou;Chen, Qincheng;Wang, Chen;Ma, Li;Shen, Guoqing research published 《 Kill three birds with one stone: Iron-doped graphitic biochar from biogas residues for ammonium persulfate activation to simultaneously degrade benzo[a]pyrene and improve lettuce growth》, the research content is summarized as follows. A graphitized magnetic biochar material, Fe-impregnated biochar (FBC), was synthesized using biogas residue, a product of food waste after anaerobic fermentation The FBC coupled with ammonium persulfate (APS) exhibited excellent performance in the catalytic degradation of benzo[a]pyrene (BaP), a pentacyclic polycyclic aromatic hydrocarbon (PAH). In the FBC-APS system, the pyrolysis temperature of biochar, the initial pH, and the FBC and APS dosages were all influencing factors for Bap degradation The FBC at the pyrolysis temperature of 700°C performed the best catalytic performance, and FBC-APS efficiently degraded BaP at a wide pH range of 3-11. Results from quenching experiments, ESR measurement, and electrochem. anal. were used as the basis to propose the possible degradation mechanisms of BaP by FBC-APS, including the radical and non-radical pathways. The radical-induced oxidation was attained by SO^·-₄ and O^·-₂. The non-radical pathway involved two aspects, one contributed by ¹O₂ and the other achieved through electron transfer. Five BaP intermediates were tentatively determined Finally, FBC-APS was applied to BaP-polluted soil, and the overall degradation rate reached 91.7% after 72 h. Lettuce growth experiment showed that FBC-APS enhanced soil nitrogen and potassium availability and lettuce growth. In summary, FBC-APS application to soil can degrade BaP, improve the manurial effect, and solve environmental problems brought by biogas residues, i.e., killing three birds with one stone.

Recommanded Product: 2,2,6,6-Tetramethyl-4-piperidinol, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid.

Li, Xuemei;Hong, Duidui;Zhang, Mengmeng;Xu, Lei;Zhou, Yubo;Li, Jia;Liu, Tao research published 《 Development of peptide epoxyketones as selective immunoproteasome inhibitors》, the research content is summarized as follows. A series of epoxyketone analogs with varying N-caps and P3-configurations were designed, synthesized and evaluated. We found that D-Ala in P3 was crucial for β5i selectivity over β5c. Notably, compounds (I) (R¹ = II) (β5i IC₅₀ = 26.0 nM, 25-fold selectivity) and I (r¹ = III) (β5i IC₅₀ = 25.1 nM, 24-fold selectivity) with the D-configuration at P3 were the most selective inhibitors. Although I (R¹ = II and III) showed only moderate anti-proliferative activity against RPMI-8226 and MM.1S cell lines, based on our experiments, it indicates that the inhibition of β5i alone is not sufficient to exert anticancer effects and may rely on the complementary inhibition of β1i, β5c and β5i. These data further increase our understanding of immunoproteasome inhibitors in hematol. malignancies.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., Recommanded Product: 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. It is a colorless liquid with an odor described as objectionable, and typical of amines. Synthetic Route of 84358-13-4.

Li, Zhan;Wang, Ke-Feng;Zhao, Xin;Ti, Huihui;Liu, Xu-Ge;Wang, Honggen research published 《 Manganese-mediated reductive functionalization of activated aliphatic acids and primary amines》, the research content is summarized as follows. In this work, a Mn-mediated reductive decarboxylative/deaminative functionalization of activated aliphatic acids and primary amines was disclosed. A series of C-X (X = S, Se, Te, H, P) and C-C bonds were efficiently constructed under simple and mild reaction conditions. The protocol was applicable to the late-stage modification of some structurally complex natural products or drugs. Preliminary mechanistic studies suggest the involvement of radicals in the reaction pathway.

Synthetic Route of 84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., 84358-13-4.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. HPLC of Formula: 5382-16-1.

Li, Zheng;Guo, Ming;Cao, Meng;Zhao, Tianming;Li, Mingzhu;Zhai, Xin research published 《 Discovery and antitumor activity of Benzo[d]imidazol-containing 2,4-diarylaminopyrimidine analogues as ALK inhibitors with mutation-combating effects》, the research content is summarized as follows. To address drug resistance caused by ALK kinase mutations, a series of novel 2,4-diarylaminopyrimidine (DAAP) analogs were designed by incorporating 1H-benzo[d]imidazol motif onto the maternal framework. All compounds were efficiently synthesized and antiproliferative activities against Karpas299, H2228 and A549 cell lines were evaluated by MTT assay. Delightly, the most promising derivative H-11 was detected with IC50 values of 0.016μM and 0.099μM against ALK- pos. Karpas299 and H2228 cells. Meanwhile, H-11 displayed encouraging enzymic inhibitory potency with IC50 values of 2.7 nM, 3.8 nM and 5.7 nM toward ALKWT, ALKL1196M and ALKG1202R, resp. Ultimately, the binding modes of optimal H-11 with ALK wild-type and mutants were ideally established which further confirmed the structural basis in accordance with the SARs anal.

HPLC of Formula: 5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 84358-13-4, formula is C11H19NO4, Name is 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic acid. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. SDS of cas: 84358-13-4.

Liu, Can;Shen, Ni;Shang, Rui research published 《 Photocatalytic decarboxylative alkylation of silyl enol ether and enamide with N-(acyloxy)phthalimide using ammonium iodide》, the research content is summarized as follows. Enamides and silyl enol ethers were alkylated to deliver products of N-acyl imines and ketones in the presence of a catalytic amount of N-tetrabutylammonium iodide (TBAI) under irradiation with purple light-emitting diodes (427 nm) at room temperature A broad scope of tertiary, secondary, and primary alkylation products was achieved with good yields and tolerance of a variety of functional groups. The reactions proceed through the photoactivation of a transiently assembled electron donor-acceptor complex formed between iodide and N-(acyloxy)phthalimide to generate alkyl radicals. The simplicity and low-cost nature of these methods without using metal catalysts demonstrate the practicality of the use of alkyl carboxylates as alkyl sources in organic synthesis.

84358-13-4, N-BOC-piperidine-4-carboxylic acid, also known asN-Boc-isonipecotic acid , is a useful research compound. Its molecular formula is C11H19NO4 and its molecular weight is 229,28 g/mole. The purity is usually 95%.

N-Boc-isonipecotic acid is a potent antitumor agent that has been clinically shown to be effective against leukemia and lymphoma. It has potent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. N-Boc-isonipecotic acid binds to the gyrase enzyme, which is used by these bacteria to maintain the integrity of their DNA, inhibiting protein synthesis and cell division. This drug also has anti-inflammatory properties. N-Boc-isonipecotic acid inhibits prostaglandin synthesis in cells, which may be due to its ability to inhibit the production of tumor necrosis factor α (TNFα) in macrophages., SDS of cas: 84358-13-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem