Zhu, Li team published research on Chemical Communications (Cambridge, United Kingdom) in 2021 | 5382-16-1

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., COA of Formula: C5H11NO

Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. COA of Formula: C5H11NO.

Zhu, Li;Zhao, Rui-Han;Li, Yu;Liu, Gong-Qing;Zhao, Yu research published 《 CtD strategy to construct stereochemically complex and structurally diverse compounds from griseofulvin》, the research content is summarized as follows. The Complexity to Diversity (CtD) strategy, for the synthesis of stereochem. complexes I (R = H, C(O)Me, Ph, Bn, etc; R1 = H, Me, n-Bu, Bn, etc.), II, III (R2 = OEt, benzyloxidanyl, morpholin-4-yl, etc.) and cis/trans-IV (R3 = H; R4 = Me, i-Pr; R3R4 = -(CH2)5-) and structurally diverse small mols. from natural products using ring-distortion reactions, was applied in the synthesis of a 47-member compounds I, II, III and cis/trans-IV collection from the natural product griseofulvin. A Tsuji-Trost allylation and oxa-Michael cyclization tandem reaction was used for the first time in the CtD strategy to generate complex ring fused cis/trans-IV .

5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., COA of Formula: C5H11NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem