On July 25, 2022, Zhou, Jimei; Jia, Minxian; Song, Menghui; Huang, Zhiliang; Steiner, Alexander; An, Qidong; Ma, Jianwei; Guo, Zhiyin; Zhang, Qianqian; Sun, Huaming; Robertson, Craig; Bacsa, John; Xiao, Jianliang; Li, Chaoqun published an article.Related Products of 39512-49-7 The title of the article was Chemoselective Oxyfunctionalization of Functionalized Benzylic Compounds with a Manganese Catalyst. And the article contained the following:
Reported in this study is a new non-heme Mn catalyst stabilized by a bipiperidine-based tetradentate ligand, which enables methylene oxidation of benzylic compounds RCH2(CH2)nCH2R1 (R = Ph, 4-chlorophenyl, 2-bromophenyl, etc.; R1 = COOH, Me, Et, etc.) by H2O2, showing high activity and excellent chemoselectivity under mild conditions. The protocol tolerates an unprecedentedly wide range of functional groups, including carboxylic acid and derivatives, ketone, cyano, azide, acetate, sulfonate, alkyne, amino acid, and amine units, thus providing a low-cost, more sustainable and robust pathway for the facile synthesis of ketones RC(O)(CH2)nCH2R1, increase of complexity of organic mols., and late-stage modification of drugs. The experimental process involved the reaction of 4-(4-Chlorophenyl)piperidin-4-ol(cas: 39512-49-7).Related Products of 39512-49-7
The Article related to aryl ketone preparation chemoselective green chem, heterocyclic preparation chemoselective green chem, aromatic hydrocarbon oxidation manganese catalyst, benzylic oxidation, cyclic imines, ketones, manganese catalysts, selective oxidation and other aspects.Related Products of 39512-49-7
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem