Mild and selective boronic acid catalyzed 1,3-transposition of allylic alcohols and Meyer-Schuster rearrangement of propargylic alcohols was written by Zheng, Hongchao;Lejkowski, Michal;Hall, Dennis G.. And the article was included in Chemical Science in 2011.Category: piperidines This article mentions the following:
Boronic acid catalysis (BAC) was applied to the transposition of allylic alcs. and a related Meyer-Schuster rearrangement of propargylic alcs. using highly electron-deficient polyfluoroarylboronic acids as catalysts under mild metal-free conditions. A wide range of synthetically useful products was formed and the synthesis of the target compounds was achieved with E:Z selectivity superior to that of metal-catalyzed methods. A mechanism is proposed involving partial or full ionization into an allylic (or propargylic) carbocation and addnl. possibilities for multicatalytic tandem reactions are exemplified. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Category: piperidines).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Category: piperidines
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem