Zhang, Wenliang’s team published research in Organic Chemistry Frontiers in 2021 | CAS: 73874-95-0

Organic Chemistry Frontiers published new progress about Amination. 73874-95-0 belongs to class piperidines, name is tert-Butyl piperidin-4-ylcarbamate, and the molecular formula is C10H20N2O2, Quality Control of 73874-95-0.

Zhang, Wenliang published the artcileAmine hydrochloride salts as bifunctional reagents for the radical aminochlorination of maleimides, Quality Control of 73874-95-0, the main research area is pyrrole dione phenyl chloro amino preparation green chem; maleimide amine radical oxidative aminochlorination copper catalyst.

Herein, a new utilization of amine hydrochloride as a bifunctional reagent was disclosed and demonstrated via the copper-catalyzed aminochlorination of maleimides I (R = Me, Ph, cyclohexyl, thiophen-2-ylmethyl, etc.). The prominent features of this transformation were found to include the simple and efficient catalyst system, broad substrate scope, readily scalable reaction, and late-stage modification of small-mol. drugs such as maprotiline hydrochloride, fluoxetine hydrochloride, nortropine hydrochloride, etc.

Organic Chemistry Frontiers published new progress about Amination. 73874-95-0 belongs to class piperidines, name is tert-Butyl piperidin-4-ylcarbamate, and the molecular formula is C10H20N2O2, Quality Control of 73874-95-0.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem