Azaphosphatranes as hydrogen-bonding organocatalysts for the activation of carbonyl groups: investigation of lactide ring-opening polymerization was written by Zhang, Dawei;Jardel, Damien;Peruch, Frederic;Calin, Nathalie;Dufaud, Veronique;Dutasta, Jean-Pierre;Martinez, Alexandre;Bibal, Brigitte. And the article was included in European Journal of Organic Chemistry in 2016.Computed Properties of C10H21N This article mentions the following:
Azaphosphatranes [N(CH2CH2NR)3PH]X (R = Me, iPr, 4-CH2C6H4OMe; X = NTf2–, BArF4–) were prepared as hydrogen-bond donors and organocatalysts for ring-opening polymerization of lactide. The hydrogen-bonding activation of C:O bonds by azaphosphatranes was explored in a model reaction, i.e., the ring-opening polymerization of lactide. The polymerization process was controlled, and allowed the preparation of polylactides with narrow dispersity under mild conditions (20 °C, 24 h, 10 mol-% catalyst loading). Interestingly, the steric hindrance of azaphosphatranes, as globular rigid structures, prevents any undesired interaction with the tertiary amine cocatalysts, as shown by x-ray anal. and semi-empirical calculations In contrast to their organocatalytic activity in the CO2/epoxide reaction, all of the phosphonium derivatives tested were found to be efficient catalysts in this ROP benchmark reaction. In the experiment, the researchers used many compounds, for example, 1,2,2,6,6-Pentamethylpiperidine (cas: 79-55-0Computed Properties of C10H21N).
1,2,2,6,6-Pentamethylpiperidine (cas: 79-55-0) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C10H21N
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem