Zalesak, Frantisek team published research on Journal of Organic Chemistry in 2021 | 5382-16-1

COA of Formula: C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. COA of Formula: C5H11NO.

Zalesak, Frantisek;Kovac, Ondrej;Lachetova, Eliska;Stastna, Nikola;Pospisil, Jiri research published 《 Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides》, the research content is summarized as follows. In this paper, a unified approach to N-substituted and N,N-disubstituted benzothiazole (BT) sulfonamides I [R = n-Bu, cyclohexyl, Bn, furan-2-ylmethyl, etc.; R1 = H, Me; RR1 = -(CH2)5-, -(CH2)2CH(OH)(CH2)2], II, III (R2 = propan-2-yl, Bn, oxiran-2-ylmethyl, etc.; RR2 = -(CH2)6-) and IV (Ar = Ph, 3-fluorophenyl, 4-chlorophenyl, etc.) was reported. The approach to BT-sulfonamides I and II starts from simple com. available building blocks (benzo[d]thiazole-2-thiol and primary and secondary amines such as allylamine, benzylamine, piperidine, etc.) that are connected via (a) a S oxidation/S-N coupling approach, (b) a S-N coupling/S-oxidation sequence, or via (c) a S-oxidation/S-F bond formation/SuFEx approach. The labile N-H bond in N-monoalkylated BT-sulfonamides III (pKa (BTSO2N(H)Bn) = 3.34 ± 0.05) further allowed to develop a simple weak base-promoted N-alkylation method and a stereoselective microwave-promoted Fukuyama-Mitsunobu reaction. N-Alkyl-N-aryl BT-sulfonamides IV were accessed with the help of the Chan-Lam coupling reaction. Developed methods were further used in stereo and chemoselective transformations of podophyllotoxin and several amino alcs. such as 3-aminopropan-1-ol and 6-aminohexan-1-ol.

COA of Formula: C5H11NO, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem