《Synthesis, characterization and antimicrobial activity of piperidine derivatives》 was published in Journal of the Chemical Society of Pakistan in 2019. These research results belong to Zafar, Shaista; Akhtar, Shamim; Ali, Syed Imran; Mushtaq, Nausheen; Naeem, Sabahat; Ali, Mohsin. Computed Properties of C6H12N2O The article mentions the following:
Synthesis of various piperidine derivatives having important biol. and pharmacol. potentials has been discussed in the past. In present study we reported the synthesis of benzoyl and sulfonyl derivatives by taking Piperidine-4-carboxamide as principal mol. These compounds were characterized by various spectroscopic techniques such as NMR, FTIR and Mass spectrometry. Elemental composition was explored using CHN analyzer. Antimicrobial activity study of the synthesized compounds was performed using disk diffusion method. Dissociation constant (pKa) of the synthesized compounds were determined by potentiometric titration method. In addition The findings of the study predicted good absorption of these newly synthesized compounds Besides, compound III showed good antifungal activity which can be helpful in pharmacokinetics and pharmacodynamics approaches of antibiotics. In the experiment, the researchers used Piperidine-4-carboxamide(cas: 39546-32-2Computed Properties of C6H12N2O)
Piperidine-4-carboxamide(cas: 39546-32-2) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Computed Properties of C6H12N2O
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem