Yang, Xiao-Guang; Du, Feng-Huan; Li, Jun-Jie; Zhang, Chi published an article in 2022. The article was titled 《Late-Stage Dehydroxyazidation of Alcohols Promoted by Trifunctional Hypervalent Azido-Iodine(III) Reagents》, and you may find the article in Chemistry – A European Journal.Related Products of 109384-19-2 The information in the text is summarized as follows:
A practical method for dehydroxyazidation of alcs. via an SN2 pathway involving PPh3 and trifunctional benziodazolone-based hypervalent azido-iodine(III) reagents, which function as an electrophilic center, an azido source and a base was reported. This mild, chemoselective method was used for late-stage azidation of structurally complex alcs., as well as for a new synthetic route to the antiepileptic drug rufinamide. The reaction mechanism was also investigated both exptl. and computationally. The experimental process involved the reaction of tert-Butyl 4-hydroxypiperidine-1-carboxylate(cas: 109384-19-2Related Products of 109384-19-2)
tert-Butyl 4-hydroxypiperidine-1-carboxylate(cas:109384-19-2) is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.Related Products of 109384-19-2
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem