Xin, Zhili published the artcileDiscovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors, Quality Control of 1032229-33-6, the publication is Bioorganic & Medicinal Chemistry Letters (2008), 18(15), 4298-4302, database is CAplus and MEDLINE.
A series of structurally novel stearoyl-Co-A desaturase 1 (SCD1) inhibitors has been identified via mol. scaffold manipulation. Preliminary structure-activity relationship (SAR) studies led to the discovery of potent, and orally bioavailable piperidine-aryl urea-based SCD1 inhibitors. 4-(2-Chlorophenoxy)-N-[3-(Me carbamoyl)phenyl]piperidine-1-carboxamide (I) exhibited robust in vivo activity with dose-dependent desaturation index lowering effects.
Bioorganic & Medicinal Chemistry Letters published new progress about 1032229-33-6. 1032229-33-6 belongs to piperidines, auxiliary class Metabolic Enzyme,SCD, name is 4-(2-Chlorophenoxy)-N-(3-(methylcarbamoyl)phenyl)piperidine-1-carboxamide, and the molecular formula is C9H21NO3, Quality Control of 1032229-33-6.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem