Titanium and Cobalt Bimetallic Radical Redox Relay for the Isomerization of N-Bz Aziridines to Allylic Amides was written by Wood, Devin P.;Guan, Weiyang;Lin, Song. And the article was included in Synthesis in 2021.HPLC of Formula: 33439-27-9 This article mentions the following:
Herein, a bimetallic radical redox-relay strategy is employed to generate alkyl radicals under mild conditions with titanium(III) catalysis and terminated via hydrogen atom transfer with cobalt(II) catalysis to enact base-free isomerizations of N-Bz aziridines I [R1R3 = (CH2)3, R2 = H; R1R2 = CH2NTsCH2CH2, R3 = H; R1 = MeO2C(CH2)7, R2 = R3 = H; etc] to N-Bz allylic amides II. This reaction provides an alternative strategy for the synthesis of allylic amides from alkenes via a three-step sequence to accomplish a formal transpositional allylic amination. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9HPLC of Formula: 33439-27-9).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.HPLC of Formula: 33439-27-9
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem