Product Details of 177-11-7. Recently I am researching about C-H ARYLATION; TETRASUBSTITUTED HELICAL ALKENES; PALLADIUM-CATALYZED ANNULATION; REGIOSELECTIVE SYNTHESIS; FUNCTIONALIZATION; ACTIVATION; ROUTE; PD/NORBORNENE; AMIDATION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [NSF 21472073, 21772075, 21532001]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhang, BS; Li, YK; Zhang, Z; An, Y; Wen, YH; Gou, XY; Quan, SQ; Wang, XG; Liang, YM. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane
Highly functionalized 4-aminoindoles were synthesized via the three-component cross-coupling of o-iodoaniline, N-benzoyloxyamines, and norbornadiene. The Catellani and retro-Diels-Alder strategy was used in this domino process. o-Iodoaniline, with electron-donating and sterically hindered protecting groups, made the reaction selective toward o-C-H amination. On the basis of density functional theory calculations, the intramolecular Buchwald coupling of this reaction underwent a dearomatization and a 1,3-palladium migration process. The reasons for the control of the chemical selectivity by the protecting groups are given. Moreover, synthetic applications toward 4-piperazinylindole and a GOT1 inhibitor were realized.
About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Zhang, BS; Li, YK; Zhang, Z; An, Y; Wen, YH; Gou, XY; Quan, SQ; Wang, XG; Liang, YM or concate me.. Product Details of 177-11-7
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Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem