Name: 1,4-Dioxa-8-azaspiro[4.5]decane. I found the field of Chemistry very interesting. Saw the article Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive published in 2020, Reprint Addresses Jin, J (corresponding author), Univ Chinese Acad Sci, Chinese Acad Sci, CAS Key Lab Synthet Chem Nat Subst, Ctr Excellence Mol Synth,Shanghai Inst Organ Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China.. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane.
An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodology features a simple Ni(II)salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides were coupled successfully with primary and secondary alkyl amines, and anilines in good to excellent yields. Similarly, benzophenone imine gave the correspondingN-arylation product in an excellent yield.
Welcome to talk about 177-11-7, If you have any questions, you can contact Han, DY; Li, SS; Xia, SQ; Su, MC; Jin, J or send Email.. Name: 1,4-Dioxa-8-azaspiro[4.5]decane
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem