The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Tris(3,5-bis(trifluoromethyl)phenyl)phosphine( cas:175136-62-6 ) is researched.Electric Literature of C24H9F18P.Koeken, Ard C. J.; van Vliet, Michiel C. A.; van den Broeke, Leo J. P.; Deelman, Berth-Jan; Keurentjes, Jos T. F. published the article 《Selectivity of rhodium-catalyzed hydroformylation of 1-octene during batch and semi-batch reaction using trifluoromethyl-substituted ligands》 about this compound( cas:175136-62-6 ) in Advanced Synthesis & Catalysis. Keywords: selectivity rhodium catalysis hydroformylation octene trifluoromethyl substituted ligand. Let’s learn more about this compound (cas:175136-62-6).
The regioselectivity of catalysts generated in situ from dicarbonyl rhodium(I)(2,4-pentanedione) and trifluoromethyl-substituted triphenylphosphine ligands has been evaluated during the hydroformylation of 1-octene. The influence of batch or semi-batch operation, the solvent, and the number of trifluoromethyl substituents has been investigated. During batch operation in a supercritical carbon dioxide (CO2)-rich system the differential n:iso ratio increases from approx. 4 to a value of 12-16 at about 90-95% conversion for the catalyst based on bis[3,5-bis(trifluoromethyl)phenyl]phenylphosphine. For semi-batch conditions using hexane a constant n:iso ratio is obtained over a broad conversion range. Batch hydroformylation in neat 1-octene is faster than in a supercritical CO2-rich, one-phase system, with a similar overall selectivity as observed in the supercritical case. The results provide further directions for the development of ligands that are especially designed for the separation of homogeneous catalysts in continuously operated hydroformylation in scCO2.
The article 《Selectivity of rhodium-catalyzed hydroformylation of 1-octene during batch and semi-batch reaction using trifluoromethyl-substituted ligands》 also mentions many details about this compound(175136-62-6)Electric Literature of C24H9F18P, you can pay attention to it, because details determine success or failure
Reference:
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