Product Details of 177-11-7. Recently I am researching about TRANSFER RADICAL-ADDITION; HECK-TYPE ALKENYLATION; TERTIARY-ALKYLATIONS; COPPER; QUINONES; ANNULATION; STRATEGY; HETEROCYCLES; REDUCTASE; COUPLINGS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21861032]; Natural Science Foundation of Yunnan ProvinceNatural Science Foundation of Yunnan Province [2018FD078]; Yunnan Local Colleges Research Projects [2017FH001-020, 2018FH001-021]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Li, DK; Shen, XF. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane
A simple and efficient Fe-catalyzed regioselective alkylation of 1,4-quinones and coumarins, using functionalized alkyl bromides as alkylating reagents, has been developed. The reaction proceeds under mild conditions with the addition of alkyl bromides to a wide range of 1,4-quinone and coumarin derivatives with a broad substrate scope and wide functional group tolerance to provide the products in good yields. Further application of these strategies could be extended to important biologically active antimalarial lead drugs, such as plasmodione on a gram scale in a single step for medicinal purposes.
Product Details of 177-11-7. About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Li, DK; Shen, XF or concate me.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem