Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 23794-15-2, is researched, Molecular C7H6ClNO, about Synthesis of some biologically active 2,4′-bipyridine-5-carbonitriles carrying the 4-hydroxyphenylthio moiety, the main research direction is bipyridine carbonitrile hydroxyphenylthio preparation antibacterial fungicide structure activity relationship.Reference of 1-(2-chloropyridine-4-yl)ethanone.
The reaction of 4-hydroxythiophenol with 4-acetyl-2-chloropyridine yielded a key intermediate, 1-{2-[(4-hydroxyphenyl)thio]pyridin-4-yl}ethanone. Further treatment of the key intermediate with Et cyanoacetate and various aromatic aldehydes in the presence of ammonium acetate furnished 4-aryl-2′-[(4-hydroxyphenyl)thio]-6-oxo-1,6-dihydro-2,4′-bipyridine-5-carbonitriles, e.g., I (R = H, MeO, Ph, Cl, Me2N). On the other hand, condensation of the key intermediate with aromatic aldehydes and malononitrile in the presence ammonium acetate of in alc. gave 6-amino-4-aryl-2′-[(4-hydroxyphenyl)thio]-2,4′-bipyridine-5-carbonitriles. All the title compounds were subjected to in vitro antibacterial testing against two strains and antifungal screening against two fungi. Some of the compounds showed promising activity.
Compounds in my other articles are similar to this one(1-(2-chloropyridine-4-yl)ethanone)Reference of 1-(2-chloropyridine-4-yl)ethanone, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem