Recommanded Product: (11bS)-4-Hydroxy-2,6-bis(4-nitrophenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (11bS)-4-Hydroxy-2,6-bis(4-nitrophenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide, is researched, Molecular C32H27N2O8P, CAS is 2129645-31-2, about An asymmetric oxidative cyclization/Mannich-type addition cascade reaction for direct access to chiral pyrrolidin-3-ones. Author is Zhou, Su; Xie, Xiongda; Xu, Xinxin; Dong, Shanliang; Hu, Wenhao; Xu, Xinfang.
An efficient gold and chiral phosphoric acid cooperatively catalyzed enantioselective oxidative cyclization/Mannich-type addition reaction of homopropargyl amides with nitrones was developed, which provided chiral pyrrolidin-3-ones I [R = Me, Et, iPr, etc.; Ar1 = Ph, 4-ClC6H4, 2-furanyl, etc.; Ar2 = Ph, 4-ClC6H4, 4-BrC6H4, etc.] in high yields with excellent enantioselectivities under mild conditions. This reaction employed stable and readily available alkynes as non-diazo carbene precursors, which provided a 100% atom economy method with high bond formation efficiency.
Compound(2129645-31-2)Recommanded Product: (11bS)-4-Hydroxy-2,6-bis(4-nitrophenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((11bS)-4-Hydroxy-2,6-bis(4-nitrophenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide), if you are interested, you can check out my other related articles.
Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem