Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products, Computed Properties of C17H24ClNO3, 120013-39-0, Name is 5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride, molecular formula is C17H24ClNO3, belongs to piperidines compound. In a document, author is Bonandi, Elisa, introduce the new discover.
Total Synthesis of (-)-Anaferine: A Further Ramification in a Diversity-Oriented Approach
The piperidine ring is a widespread motif in several natural bioactive alkaloids of both vegetal and marine origin. In the last years, a diversity-oriented synthetic (DOS) approach, aimed at the generation of a library of piperidine-based derivatives, was developed in our research group, employing commercially available 2-piperidine ethanol as a versatile precursor. Here, we report the exploration of another ramification of our DOS approach, that led us to the stereoselective total synthesis of (-)-anaferine, a bis-piperidine alkaloid present in Withania somnifera extract. This natural product was obtained in 9% overall yield over 13 steps, starting from a key homoallylic alcohol previously synthesised in our laboratory. Therefore, the collection of piperidine-derivatives accessible from 2-piperidine ethanol was enriched with a new, diverse scaffold.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 120013-39-0. Computed Properties of C17H24ClNO3.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem