Wang, Ying published the artcileThe Use of Potassium/Sodium Nitrite as a Nitrosating Agent in the Electrooxidative N-Nitrosation of Secondary Amines, Application In Synthesis of 73874-95-0, the main research area is nitroso compound preparation; secondary amine potassium nitrite electrooxidative nitrosation.
The electrochem. N-nitrosation of secondary amines, e.g., 1-phenylpiperazine using widely available sodium/potassium nitrite as a nitrosating agent has been described. This approach not only eliminates the need for using a combination of sodium/potassium and a strong acid but also has good functional group tolerance. The reaction is compatible with the late-stage modification of pharmaceutical compounds, e.g., I and could be conducted in gram scale with a high reaction efficiency. Preliminary mechanistic studies indicate that the N-nitrosation occurs via the anodic oxidation of KNO2 into an NO2 radical which is then transformed into an NO+ cation.
European Journal of Organic Chemistry published new progress about Nitrosation (electrooxidative). 73874-95-0 belongs to class piperidines, name is tert-Butyl piperidin-4-ylcarbamate, and the molecular formula is C10H20N2O2, Application In Synthesis of 73874-95-0.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem