Ring-Opening Polymerization with Lewis Pairs and Subsequent Nucleophilic Substitution: A Promising Strategy to Well-Defined Polyethylene-like Polyesters without Transesterification was written by Wang, Bin;Pan, Li;Ma, Zhe;Li, Yuesheng. And the article was included in Macromolecules (Washington, DC, United States) in 2018.Synthetic Route of C10H21N This article mentions the following:
Ring-opening polymerization (ROP) of ω-pentadecalactone (PDL) catalyzed by Lewis pairs was thoroughly explored, and a novel approach to well-defined aliphatic long chain polyester with high mol. weight (MW) was developed in the present work. The Zn(C6F5)2/1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) Lewis pair was proved to be a promising catalytic system for ROP of PDL, producing cyclic PPDL with high MW (Mw > 100 kg/mol) and relatively low polydispersity index (Mw/Mn = 1.6-1.9). Strikingly, no transesterification occurred in the ROP of PDL by Zn(C6F5)2/DBU. The cyclic topol. of the polyester could be switched to linear structure in the presence of alc. The feeding mode and the structure of alc. significantly influence the ROP. Compared with mixing alc. with Zn(C6F5)2/DBU at first, adding Ph2CHOH with low nucleophilicity after full monomer conversion could afford linear PPDL without transesterification. It was noted that random chain scission or chain extension was not detected after adding Ph2CHOH. Well-defined block copolymer containing polyethylene-like segment can be easily prepared by sequential addition of PDL and lactide (LA) or caprolactone (CL). Cyclic block copolyesters c-poly(PDL-b-CL) and c-poly(PDL-b-LA) were obtained in the absence of alc. The blocky structures can be maintained even when prolonging reaction time after full monomer conversion. Similarly, introducing Ph2CHOH before quenching the polymerization led to well-defined linear block copolyesters l-poly(PDL-b-CL) and l-poly(PDL-b-LA). In the experiment, the researchers used many compounds, for example, 1,2,2,6,6-Pentamethylpiperidine (cas: 79-55-0Synthetic Route of C10H21N).
1,2,2,6,6-Pentamethylpiperidine (cas: 79-55-0) belongs to piperidine derivatives. The piperidine structural motif is present in numerous natural alkaloids. These include piperine, which gives black pepper its spicy taste. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Synthetic Route of C10H21N
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem