Chemiluminescence detection of piperazine designer drugs and related compounds using tris(2,2′-bipyridine)ruthenium(III) was written by Waite, Rebecca J.;Barbante, Gregory J.;Barnett, Neil W.;Zammit, Elizabeth M.;Francis, Paul S.. And the article was included in Talanta in 2013.COA of Formula: C17H18F2N2 This article mentions the following:
The authors present an exploration of the chemiluminescence from reactions of benzylpiperazines and phenylpiperazines with tris(2,2′-bipyridine)ruthenium(III). The selectivity of the reagent towards these compounds was found to be highly dependent upon the pH of the solution, and the relative emission intensity was strongly influenced by electron donating or withdrawing substituents on the Ph or benzyl ring. In spite of previous investigations showing poor responses for aromatic-substituted amines (compared to their aliphatic amine counterparts), intense emissions were observed with phenylpiperazines under acidic conditions, particularly those with halogen or trifluoromethyl substituents on the aromatic ring. Buffered alk. conditions provided much broader selectivity for the detection of both phenylpiperazine and benzylpiperazine compounds, which the authors have applied to a rapid HPLC procedure for the determination of piperazines of forensic interest in ‘party pill’ samples. In the experiment, the researchers used many compounds, for example, 4,4-Difluorobenzhydrylpiperazine (cas: 27469-60-9COA of Formula: C17H18F2N2).
4,4-Difluorobenzhydrylpiperazine (cas: 27469-60-9) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.COA of Formula: C17H18F2N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics