Synthesis and transformations of the copper(II) N-(2-aminoethyl)aziridine and N-(2-haloethyl)ethylenediamine complexes was written by Ukraintsev, V. B.;Esikov, K. A.;Krasnov, B. A.;Potekhin, V. V.. And the article was included in Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) in 1997.Name: Piperazine Dihydrochloride This article mentions the following:
The Cu(II) complexes with N-(2-aminoethyl)aziridine (L’) and N-(2-haloethyl)ethylenediamine (L”) with the mol. compositions [CuLX2] and [CuL2X2] (L = L’ or L”, X = Cl or Br) were synthesized. According to the IR spectra, [CuLX2] are coordination polymers consisting of tetrahedrally distorted hexacoordinated species. [CuLBr2] disproportionates in H2O to form [CuL2Br2]. Refluxing of [CuLX2] and [CuL2X2] in BuOH results in intraspheric transformation of their L ligands into piperazine. Reaction of all the obtained Cu(II) derivatives with formaldehyde initiates formation of the piperazine ring. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Name: Piperazine Dihydrochloride).
Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by reacting alcoholic ammonia with 1,2-dichloroethane, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol.Name: Piperazine Dihydrochloride
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics