Recommanded Product: 1,4-Dioxa-8-azaspiro[4.5]decane. Recently I am researching about HYPERVALENT IODINE REAGENTS; AROMATIC NITRATION; TERTIARY-AMINES; H FUNCTIONALIZATION; CONJUGATE ADDITION; SODIUM-NITRITE; UREA NITRATE; NITROMETHANE; OXIDATION; ATOM, Saw an article supported by the Basic Science Research Program of the National Research Foundation of Korea (NRF) – Ministry of Education, Science, and Technology [2017R1E1A1A01076642]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Mudithanapelli, C; Dhorma, LP; Kim, MH. The CAS is 177-11-7. Through research, I have a further understanding and discovery of 1,4-Dioxa-8-azaspiro[4.5]decane
A novel nitration (via C(sp(3))-N breaking/C(sp(2))-N formation with CH3NO2) mediated by [bis-(trifluoroacetoxy)iodo]benzene (PIFA) is described. The NO2 transfer from CH3NO2 to the aromatic group of the substrate is possible with careful selection of the solvent, NaX, and oxidant. In addition, the solvent-controlled C(sp(2))-H functionalization can shift to an alpha-C(sp(3))-H functionalization (cyanation or oxygenation) of the alpha-C(sp(3))-H of cyclic amines.
Recommanded Product: 1,4-Dioxa-8-azaspiro[4.5]decane. Welcome to talk about 177-11-7, If you have any questions, you can contact Mudithanapelli, C; Dhorma, LP; Kim, MH or send Email.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem