Facile and clean oxidation of alcohols in water using hypervalent iodine(III) reagents was written by Tohma, Hirofumi;Maegawa, Tomohiro;Takizawa, Shinobu;Kita, Yasuyuki. And the article was included in Advanced Synthesis & Catalysis in 2002.Formula: C12H15NO3S This article mentions the following:
The facile and efficient oxidation of various alcs. such as benzylic alcs., primary alcs., secondary alcs., and diols in water using the hypervalent iodine(III) reagent, iodosobenzene (PhI:O), with KBr is described. Electrospray ionization (ESI) mass spectrometric studies on the behavior of PhI:O-KBr in aqueous solution suggested that these reactions are induced by the formation of highly reactive iodine species [PhI(Br)nO–]. Further development to recyclable polymer-supported iodine(III) reagent extends the utility of this reaction to afford an environmentally benign method. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9Formula: C12H15NO3S).
1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Formula: C12H15NO3S
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem