Synthesis of ethyleneamines. III. Pyrolysis of N,N’-bis(2-hydroxyethyl)ethylenediamine hydrochloride was written by Tkaczynski, Tadeusz. And the article was included in Acta Poloniae Pharmaceutica in 1958.COA of Formula: C4H12Cl2N2 This article mentions the following:
N,N’-Bis(2-hydroxyethyl)ethylenediamine – HCl heated 2.5 hrs. at 260° yielded piperazine-HCl (I). A similar process carried out at 200° gave I and N-piperazineëthanol-HCl (II). II on similar heating at 260° was converted into I. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3COA of Formula: C4H12Cl2N2).
Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Simple N-substituted piperazines have been found in many drug molecules. Piperazines are very broad chemical group, covering a wide range of drugs from antidepressants to antihistamines. The connecting property of all these chemicals is the presence of a piperazine functional group.COA of Formula: C4H12Cl2N2
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics