The author of 《Synthesis of 3-(5-bromo-2,3-dimethoxy-phenyl)-[1, 2, 4] oxadiazole analogues and their evaluation as anti-Parkinson’s agents》 were Tiwari, Shashi B.; Kohli, D. V.. And the article was published in Medicinal Chemistry Research in 2008. Recommanded Product: 1690-72-8 The author mentioned the following in the article:
A series of 3-(5-bromo-2,3-dimethoxy-phenyl)-[1, 2, 4] oxadiazole derivatives, e.g., I, was prepared and their evaluation for anti-Parkinson’s activity was measured in vivo using albino rats. The result of the biol. activity studies indicated that some of the synthesized compounds have good agonistic activity on the dopamine receptors and a few of them were also found to be free from neurotoxicity. Thus these compounds might be useful ligands for studying the functional role of dopamine receptors in vivo. The high log P value of the compounds indicates that they should easily cross the blood-brain barrier (log P > 2.6). In the experimental materials used by the author, we found Methyl 1-methylpiperidine-3-carboxylate(cas: 1690-72-8Recommanded Product: 1690-72-8)
Methyl 1-methylpiperidine-3-carboxylate(cas: 1690-72-8) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Recommanded Product: 1690-72-8
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem