Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 13925-03-6, Name is 2-Ethyl-6-methylpyrazine, SMILES is CC1=CN=CC(CC)=N1, belongs to piperidines compound. In a document, author is Pradhan, Sajan, introduce the new discover, Recommanded Product: 13925-03-6.
Stereoselective synthesis of 3-spiropiperidino indolenines via S(N)2-type ring opening of activated aziridines with 1H-indoles/Pd-catalyzed spirocyclization with propargyl carbonates
3-Spiropiperidino indolenines have been synthesized via novel Lewis acid-catalyzed S(N)2-type ring opening of activated aziridines with 1H-indoles followed by Pd-catalyzed dearomative spirocyclization with propargyl carbonates in up to 88% yields. The step and pot-economic transformation comprises sequential C-C, C-N, and C-C bond forming steps generating two stereogenic centers including an all-carbon quaternary stereocenter to furnish the products in diastereomerically pure (dr >99:1) forms with excellent enantiomeric excess (ee up to >99%). The synthetic versatility of the strategy has been illustrated by converting the synthesized products into spirocyclic indolenine 2-piperidinones, dihydropiperidines, and 5-alkynylated piperidines.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 13925-03-6 is helpful to your research. Recommanded Product: 13925-03-6.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem