In an article, author is Malashchuk, Andrii, once mentioned the application of 4005-49-6, Name is N-(7H-Purin-6-yl)benzamide, molecular formula is C12H9N5O, molecular weight is 239.23, MDL number is MFCD00037927, category is piperidines. Now introduce a scientific discovery about this category, Formula: C12H9N5O.
Monoprotected Diamines Derived from 1,5-Disubstituted (Aza)spiro[2.3]hexane Scaffolds
Synthesis of monoprotected diamines derived from 1,5-disubstituted spiro[2.3]hexane and 5-azaspiro[2.3]hexane scaffolds is described. In both cases, the method relied on the cyclopropanation of the corresponding cyclobutane or azetidine derivatives. In the case of monoprotected 1,5-diaminospiro[2.3]hexanes, the title products were obtained as single diastereomers. X-Ray diffraction studies supported by exit vector plot (EVP) analysis showed that the obtained building blocks are promising piperidine/cycloalkane isosteres with potential utility to drug discovery. Also, conformations observed in the crystalline state for the two different diastereomers of 1,5-diaminospiro[2.3]hexane derivatives prompt their application in design of beta-turn and sheet-like peptidomimetics, respectively.
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Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem