Cao, Q; Nicholson, WI; Jones, AC; Browne, DL in [Cao, Qun; Nicholson, William I.; Jones, Andrew C.; Browne, Duncan L.] Cardiff Univ, Sch Chem, Main Bldg,Pk Pl, Cardiff CF10 3EQ, S Glam, Wales published Robust Buchwald-Hartwig amination enabled by ball-milling in 2019, Cited 35. Formula: C7H13NO2. The Name is 1,4-Dioxa-8-azaspiro[4.5]decane. Through research, I have a further understanding and discovery of 177-11-7.
An operationally simple mechanochemical method for the Pd catalysed Buchwald-Hartwig amination of arylhalides with secondary amines has been developed using a Pd PEPPSI catalyst system. The system is demonstrated on 30 substrates and applied in the context of a target synthesis. Furthermore, the performance of the reaction under aerobic conditions has been probed under traditional solution and mechanochemical conditions, the observations are discussed herein.
Formula: C7H13NO2. Welcome to talk about 177-11-7, If you have any questions, you can contact Cao, Q; Nicholson, WI; Jones, AC; Browne, DL or send Email.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem