Tata, James R.’s team published research in Bioorganic & Medicinal Chemistry Letters in 1997-03-18 | CAS: 137419-24-0

Bioorganic & Medicinal Chemistry Letters published new progress about Structure-activity relationship. 137419-24-0 belongs to class piperidines, name is tert-Butyl spiro[indene-1,4′-piperidine]-1′-carboxylate, and the molecular formula is C18H23NO2, Synthetic Route of 137419-24-0.

Tata, James R. published the artcileThe synthesis and activity of spiroindane growth hormone secretagogues, Synthetic Route of 137419-24-0, the main research area is spiroindane preparation growth hormone secretagogue structure.

The synthesis and activities of a series of spiroindane growth hormone secretagogues is reported. Modification of the benzylic position of the spiroindane has resulted in a dramatic increase in potency resulting in sub-nanomolar peptidomimetic growth hormone secretagogues. In vivo data demonstrating the good oral activity of these analogs is reported.

Bioorganic & Medicinal Chemistry Letters published new progress about Structure-activity relationship. 137419-24-0 belongs to class piperidines, name is tert-Butyl spiro[indene-1,4′-piperidine]-1′-carboxylate, and the molecular formula is C18H23NO2, Synthetic Route of 137419-24-0.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem