Tag: M.W:200-300

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Safety of tert-Butyl (piperidin-4-ylmethyl)carbamate, Which mentioned a new discovery about 135632-53-0

AMINOPYRIMIDINE KINASE INHIBITORS

Disclosed are aminopyrimidine compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of CK1, CKIy1, CKIy2, CKIy3, CK2, Pim1, Pim2, Pim3, the TGFbeta pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of CK1, CKIy1, CKIy2, CKIy3,CK2, Pim1, Pim2, Pim3, the TGFbeta pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 135632-53-0, help many people in the next few years.Safety of tert-Butyl (piperidin-4-ylmethyl)carbamate

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17358N – PubChem

 

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 149669-43-2, molcular formula is C13H15FN2, introducing its new discovery. HPLC of Formula: C13H15FN2

SULFAMIDE-METALLOPROTEASE INHIBITORS

This invention relates to sulfamides of formula (I) STR1 that are inhibitors of metalloproteases, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C13H15FN2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 149669-43-2

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17633N – PubChem

 

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Recommanded Product: 309956-78-3, Which mentioned a new discovery about 309956-78-3

Polymorphs of a xanthine compound and its preparation method, use (by machine translation)

The invention relates to medicine field of chemical synthesis, in particular to compound 1 – [(5-fluoro -1,3-benzothiazole-2-yl) methyl] – 3-methyl-7 – (2-butyne-1-yl) – 8 – [(R) – 3-amino-piperidin-1-yl]-xanthine polymorphic form of the compound and its preparation method and its as the therapeutic drug, especially as inhibitors of dipeptidyl peptidase IV(DPP-IV) use. (by machine translation)

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Recommanded Product: 309956-78-3, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 309956-78-3

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H13386N – PubChem

 

Application of 173186-91-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.173186-91-9, Name is 1-Benzyl-3,3-dimethylpiperidin-4-one, molecular formula is C14H19NO. In a Patent£¬once mentioned of 173186-91-9

PIPERIDINE DERIVATIVES AS SEROTONINE REUPTAKE INHIBITORS

The present invention provides compounds of formula I and a method of inhibiting the reuptake of serotonin, antagonizing the 5-HT 1A receptor and antagonizing the 5-HT 2A receptor which comprises administering to a subject in need of such treatment an effective amount of a compound of formula I.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 173186-91-9 is helpful to your research. Application of 173186-91-9

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17610N – PubChem

 

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 143900-44-1, molcular formula is C10H19NO3, introducing its new discovery. Safety of (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

TYROSINE KINASE INHIBITORS

The present disclosure provides compounds and pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BLK, BMX, EGFR, HER2, HER4, ITK, TEC, BTK, and TXK and are therefore useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer and inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Safety of (S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 143900-44-1

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H14545N – PubChem

 

Chemistry is traditionally divided into organic and inorganic chemistry. HPLC of Formula: C12H13FN2O. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 84163-77-9

Thiophene compound

Thiophene compounds of the formula STR1 wherein each symbol is as defined in the specification, their pharmaceutically acceptable salts, pharmaceutical compositions containing said compound and additives for pharmaceuticals, and antipsychotics containing said compound as an active ingredient. The compound of the present invention has pharmacological actions required of antipsychotic, such as motility suppressing action, anti-apomorphine action, mothamphetamine antagonistic action, tetrabenazine-induced blepharoptosis enhancing action, and the like. The compound of the present invention is useful as an antipsychotic having less extrapyramidal side-effects or a non-benzodiazepine type antianxiety agent.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C12H13FN2O, you can also check out more blogs about84163-77-9

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H17750N – PubChem

 

Electric Literature of 236406-39-6, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 236406-39-6, Name is 8-Boc-2,8-Diazaspiro[4.5]decane, molecular formula is C13H24N2O2. In a Patent£¬once mentioned of 236406-39-6

COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY

The invention provides compounds and pharmaceutical compositions, and methods for using such compounds to treat, ameliorate or prevent a condition associated with activity of cannabinoid receptor 1 (CB1).

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Electric Literature of 236406-39-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 236406-39-6, in my other articles.

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H19489N – PubChem

 

Application of 91419-52-2, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 91419-52-2, Name is 1-Boc-4-Cyanopiperidine, molecular formula is C11H18N2O2. In a Article£¬once mentioned of 91419-52-2

Synthesis of 2,2-Dialkyl-3-halopropanenitriles from 2,2-Dialkylethanenitriles and Dihalomethanes

A simple high-yielding synthesis of 2,2-dialkyl-3-halopropanenitriles is described which involves the alkylation of 2,2-dialkylethanenitriles with bromochloromethane.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application of 91419-52-2, you can also check out more blogs about91419-52-2

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Piperidine – Wikipedia,
Piperidine | C5H15853N – PubChem

 

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 142643-29-6, name is 3-(Boc-aminomethyl)piperidine, introducing its new discovery. Recommanded Product: 3-(Boc-aminomethyl)piperidine

Solid dispersions containing an apoptosis-inducing agent

A pro-apoptotic solid dispersion comprises, in essentially non-crystalline form, a Bcl-2 family protein inhibitory compound of Formula I as defined herein, dispersed in a solid matrix that comprises (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. A process for preparing such a solid dispersion comprises dissolving the compound, the polymeric carrier and the surfactant in a suitable solvent, and removing the solvent to provide a solid matrix comprising the polymeric carrier and the surfactant and having the compound dispersed in essentially non-crystalline form therein. The solid dispersion is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 142643-29-6 is helpful to your research. Recommanded Product: 3-(Boc-aminomethyl)piperidine

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Piperidine – Wikipedia,
Piperidine | C5H16860N – PubChem

 

Related Products of 138227-63-1, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.138227-63-1, Name is tert-Butyl 4-(4-aminophenoxy)piperidine-1-carboxylate, molecular formula is C16H24N2O3. In a Patent£¬once mentioned of 138227-63-1

1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) in-hibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions containing the same, a method for treating diseases using the composition, and methods for preparing the novel compounds. The novel compounds, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present invention have histone deacetylase (HDAC) inhibitory activity and are effective for the prevention or treatment of HDAC6-mediated diseases, including infectious diseases; neoplasms; endocrine, nutritional and metabolic diseases; mental and be-havioral disorders; neurological diseases; diseases of the eye and adnexa; cardiovascular diseases; respiratory diseases; digestive diseases; diseases of the skin and subcutaneous tissue; diseases of the musculoskeletal system and connective tissue; or congenital malformations, de? formations and chromosomal abnormalities.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 138227-63-1 is helpful to your research. Related Products of 138227-63-1

Reference£º
Piperidine – Wikipedia,
Piperidine | C5H22920N – PubChem