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The present invention provides compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, methods for their preparation, methods for their use, and pharmaceutical formulations comprising them.

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Reference:
Piperidine – Wikipedia,
Piperidine | C5H15172N – PubChem

 

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4,5-Disubstituted 1,3-dithiole-2-thione salts – promising reagents for the synthesis of new tetrathiafulvanes – were obtained as a result of the reaction of bis(tetraethylammonium) bis(1,3-dithiolo-2-thiono-4,5-dithiolato)zincate with salts of beta- and gamma-haloalkylamines and omega-halo-substituted picolines.

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Piperidine – Wikipedia,
Piperidine | C5H22202N – PubChem

 

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The present invention relates to pyrazolo pyrimidine derivatives, to methods of preparing these, to combinations and pharmaceutical composition comprising these, and to their use in the treatment of diseases and disorders which may for example involve autoimmune diseases, angiogenesis, pain, and/or inflammatory diseases.

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Piperidine – Wikipedia,
Piperidine | C5H15890N – PubChem

 

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N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.

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Piperidine – Wikipedia,
Piperidine | C5H20027N – PubChem

 

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The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

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Piperidine – Wikipedia,
Piperidine | C5H19012N – PubChem

 

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Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: formula (1) or physiologically acceptable salt thereof.

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Piperidine – Wikipedia,
Piperidine | C5H18047N – PubChem

 

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The invention provides pyrazolyl guanidine compounds that inhibit F1F0-ATPase, and methods of using pyrazolyl guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer.

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Piperidine – Wikipedia,
Piperidine | C5H22752N – PubChem

 

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The present invention discloses methods of using antagonists for melanin-concentrating hormone (MCH), to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes, as well as novel compounds which are antagonists for melanin-concentrating hormone (MCH). In other aspects, the invention is directed to pharmaceutical compositions comprising such MCH antagonists as well as methods for preparing such compounds. Compounds of the invention generally have the structure: where the substituents are as defined herein.

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Piperidine – Wikipedia,
Piperidine | C5H15898N – PubChem

 

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Readily available vinyl alanes are used in the Cu-catalyzed asymmetric conjugate addition reaction to N-substituted-2-3-dehydro-4-piperidones. The enhanced reactivity of recently developed and easily prepared phosphine amine ligands in combination with inexpensive Cu(II)naphtenate (CuNp) allows the introduction of a great variety of alkenyl, alkyl, and aryl aluminums in high enantioselectivity.

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Piperidine – Wikipedia,
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Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

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Piperidine – Wikipedia,
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