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The present invention relates to an improved process for the preparation of 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)- 1 H-pyrazolo[3,4-d]pyrimidin- 1 -yl]- 1 -piperidin yl]-2-propen-1-one compound of formula- 1 and its polymorphs thereof, which is represented by the following structural formula:

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Piperidine – Wikipedia,
Piperidine | C5H14520N – PubChem

 

Discovery of 193629-39-9

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Related Products of 193629-39-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.193629-39-9, Name is N-Boc-3-(bromomethyl)piperidine, molecular formula is C11H20BrNO2. In a article,once mentioned of 193629-39-9

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

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Piperidine – Wikipedia,
Piperidine | C5H22591N – PubChem

 

Archives for Chemistry Experiments of 158407-04-6

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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Product Details of 158407-04-6, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 158407-04-6, Name is tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate, molecular formula is C11H20BrNO2. In a Patent, authors is ,once mentioned of 158407-04-6

The present application relates to compounds of formula (I), wherein A, R, R1, and R2 are as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy.

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Piperidine – Wikipedia,
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Extracurricular laboratory:new discovery of Benzyl 4-formylpiperidine-1-carboxylate

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Reference of 138163-08-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.138163-08-3, Name is Benzyl 4-formylpiperidine-1-carboxylate, molecular formula is C14H17NO3. In a Article,once mentioned of 138163-08-3

The synthesis and biological activity of novel glycoprotein IIb-IIIa anatagonists containing 3-azaspiro[5.5]undec-9-yl nucleus are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of the monoazaspirocyclic structure as central template for nonpeptide RGD mimics.

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Piperidine – Wikipedia,
Piperidine | C5H20510N – PubChem

 

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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 57611-47-9, molcular formula is C14H17NO3, introducing its new discovery. Recommanded Product: 57611-47-9

Herein, we report the synthesis and structure?activity relationship of a novel series of (R)-4,4-difluoropiperidine core scaffold as dopamine receptor 4 (D4) antagonists. A series of compounds from this scaffold are highly potent against the D4receptor and selective against the other dopamine receptors. In addition, we were able to confirm the active isomer as the (R)-enantiomer via an X-ray crystal structure.

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The Absolute Best Science Experiment for tert-Butyl piperidin-4-ylcarbamate

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Electric Literature of 73874-95-0, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 73874-95-0, name is tert-Butyl piperidin-4-ylcarbamate. In an article,Which mentioned a new discovery about 73874-95-0

The present invention relates to beta-amino acid derivatives as dipeptidyl peptidase- IV inhibitors and the processes for the synthesis of the same. This invention also relates to pharmacological compositions containing the compounds of the present invention, and methods of treating diabetes, especially type 2 diabetes, as well as prediabetes, diabetic dyslipidemia, metabolic acidosis, ketosis, satiety disorders, and obesity. These inhibitors can also be used to treat conditions manifested by a variety of metabolic, neurological, anti-inflammatory, and autoimmune disorders like inflammatory disease, multiple sclerosis, rheumatoid arthritis; viral, cancer and gastrointestinal disorders. The compounds of this invention can also be used for treatment of infertility arising due to polycystic ovary syndrome.

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Piperidine – Wikipedia,
Piperidine | C5H13834N – PubChem

 

More research is needed about 56346-57-7

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Related Products of 56346-57-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.56346-57-7, Name is (4-Fluorophenyl)(piperidin-4-yl)methanone, molecular formula is C12H14FNO. In a Article,once mentioned of 56346-57-7

A novel series of anti-malarials, based on a hydroxy-ethyl-amine scaffold, initially identified as peptidomimetic protease inhibitors is described. Combination of the hydroxy-ethyl-amine anti-malarial phramacophore with the known Mannich base pharmacophore of amodiaquine (57) resulted in promising in vivo active novel derivatives.

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Brief introduction of 137076-22-3

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Compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and/or mutant c-kit protein kinases.

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Piperidine – Wikipedia,
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Ezetimibe (Zetia), a cholesterol-absorption inhibitor (CAI) approved by the FDA for the treatment of hypercholesterolemia, is believed to target the intestine protein Niemann-Pick C1-Like 1 (NPC1L1) or its pathway. A spiroimidazolidinone NPC1L1 inhibitor identified by virtual screening showed moderate binding activity but was not efficacious in an in vivo rodent model of cholesterol absorption. Synthesis of analogs established the structure-activity relationships for binding activity, and resulted in compounds with in vivo efficacy, including 24, which inhibited plasma cholesterol absorption by 67% in the mouse, thereby providing proof-of-concept that non-beta-lactams can be effective CAIs.

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Piperidine – Wikipedia,
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The present invention relates to a new piperidine inhibitors of Janus Kinase 3 activity, pharmaceutical compositions thereof, and methods of use there-of.

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Piperidine – Wikipedia,
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