Tag: M.W:100-200

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Recommanded Product: 106-52-5, Which mentioned a new discovery about 106-52-5

The present disclosure discloses a modified compound of andrographolide, and particularly discloses a compound shown in formula (I) and (II) or a pharmaceutically acceptable salt thereof.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H2371N – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 68947-43-3, name is 1-Methylpiperidine-4-carboxylic acid, introducing its new discovery. name: 1-Methylpiperidine-4-carboxylic acid

Provided are prodrugs of (S) -or (R) -ketamine, including isotopically labeled ketamine,composition and uses thereof. Compounds having formula (Ia) or (Ib) as the prodrugs of (S) -or (R) -ketamine, including isotopically labeled ketamine, and pharmaceutical compositions comprising the compounds provided herein are used for treating or preventing a CNS disease.More particularly, the related diseases include depression and pain. (Ia) (Ib)

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 68947-43-3 is helpful to your research. name: 1-Methylpiperidine-4-carboxylic acid

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Piperidine – Wikipedia,
Piperidine | C5H6940N – PubChem

Electric Literature of 3040-44-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 3040-44-6, Name is 1-(2-Hydroxyethyl)piperidine,introducing its new discovery.

A series of 2-(2-aminoethoxy)-1-phenylethanols having a variety of N- and phenyl-substitution patterns as well as 5- and 6-membered heteroaryl counterparts of our prototype compound 1 (2-(2-dimethylaminoethoxy)-1- phenylethanol) have been prepared and evaluated for antiamnestic and antihypoxic activities. Compound 3b, the 3-methylphenyl analogue of 1, proved to be significantly more potent than I in reversing electroconvulsive shock- induced amnesia as well as CO2-induced learning-impairment in mice. It exhibited low acute toxicity in mice and afforded a greater brain/serum concentration ratio than 1 after oral administration to rats.

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Piperidine – Wikipedia,
Piperidine | C5H5436N – PubChem

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， SDS of cas: 21987-29-1, Which mentioned a new discovery about 21987-29-1

The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)

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Piperidine – Wikipedia,
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Chemistry is an experimental science, Safety of Piperidin-4-ol hydrochloride, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 5382-17-2, Name is Piperidin-4-ol hydrochloride

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).

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Piperidine – Wikipedia,
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Chemistry is traditionally divided into organic and inorganic chemistry. Computed Properties of C6H13NO. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 106-52-5

The present invention relates to pharmaceutical agents of formula (I) useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF- KB-inducing kinase (NIK – also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.

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Piperidine – Wikipedia,
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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 657-36-3, name is 4-Trifluoromethylpiperidine, introducing its new discovery. Recommanded Product: 657-36-3

The invention relates to novel 8-arylalkyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepines of general formula 1 which are useful in the prevention or treatment of HIV infection.

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Piperidine – Wikipedia,
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Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 5437-48-9, molcular formula is C7H15ClN2O, introducing its new discovery. category: piperidines

The intramolecular oxymercuration of the 1-(2-tetrahydrofuryl)-4-penten-1-ols (5) by mercuric salts followed by reductive demercuration affords the 2-methyl-5-tetrahydrofuryltetrahydrofuran (9) as a mixture of cis and trans isomers in good yields.By using mercuric acetate, each isomer threo 5a and erythro 5b gives the trans isomer, 9d and 9b, respectively, as the major products.On the other hand, cyclization carried out with mercuric chloride are not stereoselective.

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Piperidine – Wikipedia,
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A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Application In Synthesis of 1,4-Dioxa-8-azaspiro[4.5]decane, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 177-11-7, Name is 1,4-Dioxa-8-azaspiro[4.5]decane, molecular formula is C7H13NO2. In a Patent, authors is ，once mentioned of 177-11-7

This invention relates to a process for the catalytic hydrolysis of an alpha-aminonitrile in the heterogeneous phase, and to polymeric resins having a catalytic activity for carrying out the present process. The process according to this invention is characterized in that said alpha-aminonitrile or one of the salts thereof is reacted in an aqueous medium, in the heterogeneous phase and in the presence of hydroxide ions on a polymeric resin which contains side chains carrying a carbonyl group, and which is insoluble in the aqueous basic medium.

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Reference of 68947-43-3, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 68947-43-3, Name is 1-Methylpiperidine-4-carboxylic acid, molecular formula is C7H13NO2. In a Article，once mentioned of 68947-43-3

A new series of 4-aminopyridyl-based lead inhibitors targeting Trypanosoma cruzi CYP51 (TcCYP51) has been developed using structure-based drug design as well as structure-property relationship (SPR) analyses. The screening hit starting point, LP10 (KD ? 42 nM; EC50 = 0.65 muM), has been optimized to give the potential leads 14t, 27i, 27q, 27r, and 27t, which have low-nanomolar binding affinity to TcCYP51 and significant activity against T. cruzi amastigotes cultured in human myoblasts (EC50 = 14-18 nM for 27i and 27r). Many of the optimized compounds have improved microsome stability, and most are selective against human CYPs 1A2, 2D6, and 3A4 (<50% inhibition at 1 muM). A rationale for the improvement in microsome stability and selectivity of inhibitors against human metabolic CYP enzymes is presented. In addition, the binding mode of 14t with the Trypanosoma brucei CYP51 (TbCYP51) orthologue has been characterized by X-ray structure analysis. Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Reference of 68947-43-3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 68947-43-3, in my other articles.

Reference：
Piperidine – Wikipedia,
Piperidine | C5H6988N – PubChem