Tag: M.W:100-200

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Product Details of 1484-84-0, Which mentioned a new discovery about 1484-84-0

Amine-functionalized mesoporous silica is one of the most promising solid sorbents for CO2 capture. The pore structure of sorbents plays a crucial role in enhancing sorption and desorption kinetics. In this work, mesoporous silica nanosphere (MSN) with inverted cone-shaped pore structure was synthesized and examined as the support for polyethyleneimine (PEI). The unique pore structure of MSN support for PEI resulted in significantly faster sorption and desorption rates and higher sorption capacity within short sorption time when compared to the benchmark support SBA-15 with the same amount of PEI loading. With 65 wt% PEI loading, 65PEI/MSN sorbent showed about 50% higher working capacity, together with 27% faster rate of CO2 sorption and 71% faster rate of CO2 desorption, compared to that with 65PEI/SBA-15 in sorption/desorption cycles. PEI/MSN sorbents have great potential for practical applications in CO2 capture.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H5673N – PubChem

Reference of 177-11-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.177-11-7, Name is 1,4-Dioxa-8-azaspiro[4.5]decane, molecular formula is C7H13NO2. In a Article，once mentioned of 177-11-7

Curative interferon and ribavirin sparing treatments for hepatitis C virus (HCV)-infected patients require a combination of mechanistically orthogonal direct acting antivirals. A shared component of these treatments is usually an HCV NS5A inhibitor. First generation FDA approved treatments, including the component NS5A inhibitors, do not exhibit equivalent efficacy against HCV virus genotypes 1-6. In particular, these first generation NS5A inhibitors tend to select for viral drug resistance. Ombitasvir is a first generation HCV NS5A inhibitor included as a key component of Viekira Pak for the treatment of patients with HCV genotype 1 infection. Since the launch of next generation HCV treatments, functional cure for genotype 1-6 HCV infections has been achieved, as well as shortened treatment duration across a wider spectrum of genotypes. In this paper, we show how we have modified the anchor, linker, and end-cap architecture of our NS5A inhibitor design template to discover a next generation NS5A inhibitor pibrentasvir (ABT-530), which exhibits potent inhibition of the replication of wild-type genotype 1-6 HCV replicons, as well as improved activity against replicon variants demonstrating resistance against first generation NS5A inhibitors.

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Piperidine – Wikipedia,
Piperidine | C5H7626N – PubChem

Reference of 1121-89-7, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1121-89-7, Name is Piperidine-2,6-dione, molecular formula is C5H7NO2. In a Article，once mentioned of 1121-89-7

A new method of transamidation of carboxamides with amines catalyzed by benzotriazole has been developed.

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Piperidine – Wikipedia,
Piperidine | C5H1540N – PubChem

Synthetic Route of 430461-56-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.430461-56-6, Name is (R)-3-Phenylpiperidine, molecular formula is C11H15N. In a article，once mentioned of 430461-56-6

The invention relates to compounds of the formulae (I), (II) and (III) in which R1, R2, R3, R4, Y, W1, W2, L, A, Alk, Cyc, Ar, Het1, Het2, Hal and n have the meaning indicated in claim 1, and/or physiologically acceptable salts, tautomers and stereo-isomers thereof, including mixtures thereof in all ratios. The compounds of the formula (I) can be used for the inhibition of serine/threonine protein kinases and for the sensitisation of cancer cells to anticancer agents and/or ionising radiation. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of cancer, tumours, metastases or angiogenesis disorders, in combination with radiotherapy and/or an anticancer agent. The invention furthermore relates to a process for the preparation of the compounds of the formula (I) by reaction of compounds of the formulae (II) and (III) and optionally conversion of a base or acid of the compounds of the formula (I) into one of their salts.

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Piperidine – Wikipedia,
Piperidine | C5H9234N – PubChem

Electric Literature of 27578-60-5, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 27578-60-5, Name is N-(2-Aminoethyl)piperidine,introducing its new discovery.

A series of structurally similar oxovanadium(V) complexes with analogous Schiff bases have been prepared and structurally characterized. The urease inhibitory activities of the complexes were investigated. The shorter the terminal groups of the Schiff base ligands are, the stronger the urease inhibitory activities of the oxovanadium(V) complexes.

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Piperidine – Wikipedia,
Piperidine | C5H4712N – PubChem

Reference of 41838-46-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.41838-46-4, Name is 4-Amino-1-methylpiperidine, molecular formula is C6H14N2. In a Article，once mentioned of 41838-46-4

The transcriptional repressor B-cell lymphoma 6 (BCL6) is frequently misregulated in diffuse large B-cell lymphoma (DLBCL) and has emerged as an attractive drug target for the treatments of lymphoma. In this article, a series of N-phenyl-4-pyrimidinamine derivatives were designed and synthesized as potent BCL6 inhibitors by optimizing hit compound N4-(3-chloro-4-methoxyphenyl)-N2-isobutyl-5-fluoro-2,4-pyrimidinediamine on the basis of the structure-activity relationship. Among them, compound 14j displayed the most potent activities, which significantly blocked the interaction of BCL6 with its corepressors, reactivated BCL6 target genes in a dose-dependent manner, and had better effects compared with the two positive controls. Further studies indicated that a low dose of 14j could effectively inhibit germinal center formation. More importantly, 14j not only showed potent inhibition of DLBCL cell proliferation in vitro but also strongly suppressed the growth of DLBCL in vivo.

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Piperidine – Wikipedia,
Piperidine | C5H1707N – PubChem

Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 106-52-5, molcular formula is C6H13NO, introducing its new discovery. SDS of cas: 106-52-5

The present invention relates to cancer therapies using novel anticancer agents with a specific mechanism of action. The invention also relates to novel chemical compounds and their therapeutic application in man.

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Piperidine – Wikipedia,
Piperidine | C5H2323N – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. Recommanded Product: 41979-39-9. The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 41979-39-9

New heterocyclic compounds that may be used to modulate a histamine receptor in an individual are described. Pyrido[4,3-b]indoles are described, as are pharmaceutical compositions comprising the compounds and methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

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Reference：
Piperidine – Wikipedia,
Piperidine | C5H6055N – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Recommanded Product: 2-Piperidineethanol, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1484-84-0, Name is 2-Piperidineethanol, molecular formula is C7H15NO. In a Article, authors is Passarella, Daniele，once mentioned of 1484-84-0

(figure presented) Total synthesis of aloperine and 6-epj-aloperine is reported. The crucial steps of the synthetic strategy are an aza-annulation reaction and an intermolecular Diels-Alder reaction. The synthetic plan proceeds from commercially available piperidine-2-ethanol.

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Piperidine – Wikipedia,
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Electric Literature of 142752-12-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.142752-12-3, Name is 1-(4-Aminophenyl)piperidin-4-ol, molecular formula is C11H16N2O. In a Patent，once mentioned of 142752-12-3

The present invention relates to novel pyrimide derivatives of formula (I): that are useful as kinase inhibitors. More particularly, the present invention relates to novel pyrimidine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders

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Piperidine – Wikipedia,
Piperidine | C5H12849N – PubChem