439811-37-7, 1-Boc-4-(4-Bromobenzoyl)piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of 1 g (3.15 mmol) of compound 5a in 10 mL of THF was added 1.3 mL (3.25 mmol) of n-BuLi at -78 C. After 20 min, a solution of 0.92 g (2.5 mmol) of compound 8 was added and the mixture was warmed to 0 C. over 1 h. It was quenched with 50 mL of H2O and extracted with three 70 mL portions of dichloromethane. The combined organic extracts were washed with 30 mL of brine, and concentrated. The residue was purified by silica gel chromatography eluting with a gradient from 1 to 3% methanol in dichloromethane containing 1% NH4OH to give 1.7 g of compound 9a.
439811-37-7 1-Boc-4-(4-Bromobenzoyl)piperidine 22890526, apiperidines compound, is more and more widely used in various.
Reference£º
Patent; Schering Corporation; US2005/49269; (2005); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem