Tag: 285.34

Various Physical Properties of Piperic Acid: A Potential Biomaterial for Future Electronics Applications was written by Gowsia, Ishrat;Mir, Feroz A.;Banday, Javid A.. And the article was included in Journal of Electronic Materials.SDS of cas: 94-62-2 This article mentions the following:

Alk. hydrolysis of piperine yields piperic acid, which has been studied for its structural, optical, and thermal properties. X-ray diffraction studies revealed an orthorhombic crystal structure for the compound Morphol. studies carried out by SEM revealed that the compound has a fibrous structure. Fourier-transform IR spectroscopy confirms its associated vibrational groups at expected positions. In its UV-visible spectrum, the compound displayed direct forbidden and indirect allowed transitions. The optical band gap (Eg) was calculated at around 3.42 eV, indicating that indirect allowed transitions are followed by the compound Photoluminescence studies show that, with excitation in the UV region, the compound emits in the violet and red regions of the visible spectrum. M.p., stability, and other important thermodn. parameters were obtained from thermal studies of the compound Various properties shown by the compound have also been compared with piperine (parent compound). Piperic acid shows a significant improvement in these properties in comparison with piperine. Both piperine and piperic acid were subjected to theor. calculations using d. function theory. These theor. calculations and exptl. results mostly correlate with each other. Further, as per the observed properties, a diode-like structure of piperic acid was prepared and characterized for elec. properties under various illumination conditions displaying good rectifying behavior. Variation of capacitance and loss of this device was also studied and is briefly explained. The studies carried out on piperic acid project it a suitable candidate for optoelectronic device operation. In the experiment, the researchers used many compounds, for example, (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2SDS of cas: 94-62-2).

(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Piperidine derivatives are being utilized in different ways as anticancer, antiviral, antimalarial, antimicrobial, antifungal, antihypertension, analgesic, anti-inflammatory, anti-Alzheimer, antipsychotic and/or anticoagulant agents.SDS of cas: 94-62-2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Evaluation of Piperine as Natural Coformer for Eutectics Preparation of Drugs Used in the Treatment of Cardiovascular Diseases was written by Wilhelm-Romero, Krissia;Quiros-Fallas, Maria Isabel;Vega-Baudrit, Jose Roberto;Guillen-Giron, Teodolito;Vargas-Huertas, Felipe;Navarro-Hoyos, Mirtha;Araya-Sibaja, Andrea Mariela. And the article was included in AAPS PharmSciTech in 2022.SDS of cas: 94-62-2 This article mentions the following:

Piperine (PIP) was evaluated as a natural coformer in the preparation of multicomponent organic materials for enhancing solubility and dissolution rate of the poorly water-soluble drugs: curcumin (CUR), lovastatin (LOV), and irbesartan (IBS). A screening based on liquid assisted grinding technique was performed using 1:1 drug-PIP molar ratio mixtures, followed by differential scanning calorimetry (DSC) and powder X-ray diffraction (PXRD) anal. Three eutectic mixtures (EMs) composed of CUR-PIP, LOV-PIP, and IBS-PIP were obtained. Therefore, binary phase and Tamman′s diagrams were constructed for each system to obtain the exact eutectic composition, which was 0.41:0.59, 0.29:0.71, and 0.31:0.69 for CUR-PIP, LOV-PIP, and IBS-PIP, resp. Further, bulk materials of each system were prepared to characterize them through DSC, PXRD fully, Fourier transform IR spectroscopy (FT-IR), and solution-state NMR (NMR) spectroscopy. In addition, the contact angle, solubility, and dissolution rate of each system were evaluated. The preserved characteristic in the PXRD patterns and FT-IR spectra of the bulk material of each system confirmed the formation of EM mixture without mol. interaction in solid-state. The formation of EM resulted in improved aqueous solubility and dissolution rate associated with the increased wettability observed by the decrease in contact angle. In addition, solution NMR analyses of CUR-PIP, LOV-PIP, and IBS-PIP suggested no significant intermol. interactions in solution between the components of the EM. Hence, this study concludes that PIP could be an effective coformer to improve the solubility and dissolution rate of CUR, LOV, and IBS. In the experiment, the researchers used many compounds, for example, (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2SDS of cas: 94-62-2).

(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2) belongs to piperidine derivatives.Piperidine is a key saturated heterocyclic scaffold found in several of the top-selling small molecule pharmaceuticals and natural alkaloids, with a diverse range of biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.SDS of cas: 94-62-2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

Application of ohmic heating for black pepper (Piper nigrum L.) oleoresin extraction compared with conventional heating was written by Induruwa Vidana Arachchige Don, Chaminda Sampath Induruwa;Jittanit, Weerachet;Lorjaroenphon, Yaowapa. And the article was included in Journal of Food Processing and Preservation in 2022.Safety of (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one This article mentions the following:

The aims of this research were to investigate the possibility of applying ohmic heating for assisting in solvent extraction of black pepper oleoresin and to compare the yield and quality of oleoresin with that obtained from the conventional heating method. The elec. conductivities were measured of black pepper powder mixed with different solvents and the residues from each extraction stage. The extraction was conducted in two stages using a black pepper powder-to-solvent ratio of 1:10. The elec. conductivities of the black pepper powder and residue mixtures ranged from 0.01 to 0.17 S/m depending on the ethanol-to-distilled water ratio and extraction stage. Ohmic heating extraction significantly improved the oleoresin yield and piperine content compared to conventional heating. The microstructures of the powder and residues obtained after extraction indicated that ohmic heating caused pores and fractures in the cell walls of black pepper cells that facilitated solvent and oleoresin transfer. Novelty impact statement : This study revealed that the elec. conductivity is an indicator of the oleoresin content in the black pepper powder and raffinate. Moreover, ohmic heating has potential for the com. extraction of black pepper oleoresin and provided scientific evidence of yield and quality improvement. The application of ohmic heating-assisted extraction could broaden the technol. for extracting spice oleoresins in the food industry. In the experiment, the researchers used many compounds, for example, (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2Safety of (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one).

(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one (cas: 94-62-2) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.Safety of (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem