252882-60-3, 1′-Boc-1,2-dihydro-2-oxo-spiro[3H-indole-3,4′-piperidine] is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate A (1g, 3.31 mmol) and N-brotnosuccinimide (0.618 g, 3.47 mmol) were dissolved in DMF (20 ml) and stirred at ambient temperetaure for 20h, and then combined with cold water (250mL). A white precipitate was collected by filtration, the solids rinsed with additional 100mL of water and dried in desiccator. Purification by a column chromatography using Biotage 40M, eluent: hexanes/ethyl acetate 0-60%/1.3 L provided the desired product, LCMS (Method B): 3.41mm, m/z (MNa)+ = 402.9/404.9.
252882-60-3 1′-Boc-1,2-dihydro-2-oxo-spiro[3H-indole-3,4′-piperidine] 21268375, apiperidines compound, is more and more widely used in various.
Reference£º
Patent; MERCK & CO., INC.; WO2008/144266; (2008); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem