Tag: 232.3214

Nemak, Katalin et al. published their research in Tetrahedron in 1996 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 27262-40-4

Study of the diastereoisomers formed between pipecolic acid N-alkylanilides and 2R,3R-tartaric acid or O,O’-dibenzoyl-2R,3R-tartaric acid. Do the tartaric acids form molecular complexes instead of salts during optical resolutions? was written by Nemak, Katalin;Acx, Maria;Jaszay, Zsuzsa M.;Kozma, David;Fogassy, Elemer. And the article was included in Tetrahedron in 1996.Recommanded Product: 27262-40-4 This article mentions the following:

During the title resolutions the precipitated diastereoisomer was not the salt but a diastereoisomeric complex in 8 cases from 13. The results indicate that tartaric acids may be used as general resolving agents for optical resolution of racemates even having no basic group. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Recommanded Product: 27262-40-4).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 27262-40-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Nemak, Katalin et al. published their research in Tetrahedron in 1996 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 27262-40-4

Study of the diastereoisomers formed between pipecolic acid N-alkylanilides and 2R,3R-tartaric acid or O,O’-dibenzoyl-2R,3R-tartaric acid. Do the tartaric acids form molecular complexes instead of salts during optical resolutions? was written by Nemak, Katalin;Acx, Maria;Jaszay, Zsuzsa M.;Kozma, David;Fogassy, Elemer. And the article was included in Tetrahedron in 1996.Recommanded Product: 27262-40-4 This article mentions the following:

During the title resolutions the precipitated diastereoisomer was not the salt but a diastereoisomeric complex in 8 cases from 13. The results indicate that tartaric acids may be used as general resolving agents for optical resolution of racemates even having no basic group. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Recommanded Product: 27262-40-4).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Recommanded Product: 27262-40-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Enquist, Muerit et al. published their research in Journal of Chromatography in 1990 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising 伪-glucosidase inhibitors. The former are analogs of DNJ with an improved 伪-glucosidase inhibitory profile than that of DNJ. Boisson et al.Computed Properties of C14H20N2O

Influence of uncharged mobile phase additives on retention and enantioselectivity of chiral drugs using an 伪1-acid glycoprotein column was written by Enquist, Muerit;Hermansson, Joergen. And the article was included in Journal of Chromatography in 1990.Computed Properties of C14H20N2O This article mentions the following:

The effect of uncharged mobile phase additives on retention and enantioselectivity on a chiral 伪1-acid glycoprotein (AGP) column was investigated. Chiral selectivity for several drugs can be induced by adding to the mobile phase uncharged modifiers with different hydrophobicities and different hydrogen bonding properties. Modifiers with different hydrogen bonding properties affect the enantioselectivity in different ways. The solute enantiomers seem to compete with the modifier mols. for binding to the chiral stationary phase. The adsorption of PrOH and MeCN on the AGP column was measured. A monolayer was obtained at mobile phase concentrations of 1.3M (10%) and 2.8M (15%) for AcOH and MeCN, resp. These concentrations are in the ranges usually used for chromatog. studies. The effect of 2-propanol on the protein conformation was studied using CD spectroscopy. It was not possible to detect any changes in the conformation of AGP, even in the presence of 40% 2-propanol. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Computed Properties of C14H20N2O).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising 伪-glucosidase inhibitors. The former are analogs of DNJ with an improved 伪-glucosidase inhibitory profile than that of DNJ. Boisson et al.Computed Properties of C14H20N2O

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Romero, Donna L. et al. published their research in Journal of Medicinal Chemistry in 1996 | CAS: 50534-23-1

N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Product Details of 50534-23-1

Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors was written by Romero, Donna L.;Olmsted, Robert A.;Poel, Toni Jo;Morge, Raymond A.;Biles, Carolyn;Keiser, Barbara J.;Kopta, Laurice A.;Friis, Jan M.;Hosley, John D.. And the article was included in Journal of Medicinal Chemistry in 1996.Product Details of 50534-23-1 This article mentions the following:

A novel class of bis(heteroaryl)piperazine (BHAP) analogs which possesses the ability to inhibit NNRTI (non-nucleoside reverse transcriptase inhibitor) resistant recombinant HIV-1 reverse transcriptase (RT) and NNRTI resistant variants of HIV-1 was identified via targeted screening. Further investigation of the structure-activity relationships of close congeners of these novel (alkylamino)piperidine BHAPs (AAP-BHAPs) led to the synthesis of several compounds possessing the desired phenotype (e.g., activity against recombinant RTs carrying the Y181C and P236L substitutions). Further structural modifications were required to inhibit metabolism and modulate solubility in order to obtain compounds with the desired biol. profile as well as appropriate pharmaceutical properties. The AAP-BHAPs with the most suitable characteristics were compounds I and II. In the experiment, the researchers used many compounds, for example, N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1Product Details of 50534-23-1).

N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Product Details of 50534-23-1

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Abdel-Rehim, Mohamed et al. published their research in Journal of Microcolumn Separations in 2001 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Application of 27262-40-4

Determination of ropivacaine and its metabolites in human plasma using solid phase microextraction and GC-NPD / GC-MS was written by Abdel-Rehim, Mohamed;Andersson, Mikael;Portelius, Erik;Norsten-Hoog, Carina;Blomberg, Lars G.. And the article was included in Journal of Microcolumn Separations in 2001.Application of 27262-40-4 This article mentions the following:

The performance of solid-phase microextraction (SPME) in combination with capillary gas chromatog. (CGC) to quantify ropivacaine and its metabolites in human plasma was studied. The anal. was performed using either a N P detector (NPD) or a mass-spectrometric detector. For extraction, Carbowax / divinylbenzene, polyacrylate and polydimethylsiloxane fibers were tested. Absorption and desorption times were studied for all analytes sep. The Carbowax / divinylbenzene fiber gave the highest recovery in plasma samples as compared to the other fibers. The effects of temperature, addition of salt, and agitation of the sample were studied. The validation of the method showed that the chromatog. selectivity was satisfactory and all metabolites were well separated SPME gave higher deviation as compared to published data for solid-phase and liquid-liquid extraction as sample preparation methods but the acceptance criteria for the study validation were well in line with the international criteria. The major disadvantage of SPME in quant. bioanal. is that the fiber does not withstand a complete run (standards + blanks + QC samples + patient samples). Also, the quality of fiber and the fiber length can differ from batch to batch. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Application of 27262-40-4).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Application of 27262-40-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Wolrab, Denise et al. published their research in Journal of Separation Science in 2013 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

Click chemistry immobilization strategies in the development of strong cation exchanger chiral stationary phases for HPLC was written by Wolrab, Denise;Fruehauf, Peter;Kohout, Michal;Lindner, Wolfgang. And the article was included in Journal of Separation Science in 2013.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide This article mentions the following:

Enantioseparation of chiral amines with HPLC has developed into a widely used anal. and preparative tool. Chiral basic mols., which act as cationic species upon protonation, are suited for an enantioselective cation exchange process. Novel strong cation exchangers (SCX) based on different 3,5-disubstituted benzoic acids functionalized with trans-(R,R)- and trans-(S,S)-2-aminocyclohexanesulfonic acid as the chiral selector (SO) and ion exchange unit were synthesized. Employing 1,3-dipolar cycloaddition (azide-yne click chem.), the SOs were immobilized onto azidopropyl-modified silica gel. This immobilization strategy enables controlled loading of the SO, and especially, high SO d. on the silica surface compared to the thiol-ene click immobilization. The performance of the novel SCX chiral stationary phases was evaluated under polar organic mode conditions with different ratios of methanol and acetonitrile, thereby changing the polarity of the bulk mobile phase. The type of co- and counterion additives employed in the mobile phase was varied as well. The influence of the formed 1,2,3-triazol spacer as well as different substitution patterns in the benzene unit on the chiral recognition properties of the SOs is discussed. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Enquist, Muerit et al. published their research in Journal of Chromatography in 1990 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Computed Properties of C14H20N2O

Influence of uncharged mobile phase additives on retention and enantioselectivity of chiral drugs using an α1-acid glycoprotein column was written by Enquist, Muerit;Hermansson, Joergen. And the article was included in Journal of Chromatography in 1990.Computed Properties of C14H20N2O This article mentions the following:

The effect of uncharged mobile phase additives on retention and enantioselectivity on a chiral α1-acid glycoprotein (AGP) column was investigated. Chiral selectivity for several drugs can be induced by adding to the mobile phase uncharged modifiers with different hydrophobicities and different hydrogen bonding properties. Modifiers with different hydrogen bonding properties affect the enantioselectivity in different ways. The solute enantiomers seem to compete with the modifier mols. for binding to the chiral stationary phase. The adsorption of PrOH and MeCN on the AGP column was measured. A monolayer was obtained at mobile phase concentrations of 1.3M (10%) and 2.8M (15%) for AcOH and MeCN, resp. These concentrations are in the ranges usually used for chromatog. studies. The effect of 2-propanol on the protein conformation was studied using CD spectroscopy. It was not possible to detect any changes in the conformation of AGP, even in the presence of 40% 2-propanol. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Computed Properties of C14H20N2O).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. The piperidine and polyhydroxylated indolizidine derivatives have shown to be promising α-glucosidase inhibitors. The former are analogs of DNJ with an improved α-glucosidase inhibitory profile than that of DNJ. Boisson et al.Computed Properties of C14H20N2O

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Romero, Donna L. et al. published their research in Journal of Medicinal Chemistry in 1996 | CAS: 50534-23-1

N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Product Details of 50534-23-1

Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors was written by Romero, Donna L.;Olmsted, Robert A.;Poel, Toni Jo;Morge, Raymond A.;Biles, Carolyn;Keiser, Barbara J.;Kopta, Laurice A.;Friis, Jan M.;Hosley, John D.. And the article was included in Journal of Medicinal Chemistry in 1996.Product Details of 50534-23-1 This article mentions the following:

A novel class of bis(heteroaryl)piperazine (BHAP) analogs which possesses the ability to inhibit NNRTI (non-nucleoside reverse transcriptase inhibitor) resistant recombinant HIV-1 reverse transcriptase (RT) and NNRTI resistant variants of HIV-1 was identified via targeted screening. Further investigation of the structure-activity relationships of close congeners of these novel (alkylamino)piperidine BHAPs (AAP-BHAPs) led to the synthesis of several compounds possessing the desired phenotype (e.g., activity against recombinant RTs carrying the Y181C and P236L substitutions). Further structural modifications were required to inhibit metabolism and modulate solubility in order to obtain compounds with the desired biol. profile as well as appropriate pharmaceutical properties. The AAP-BHAPs with the most suitable characteristics were compounds I and II. In the experiment, the researchers used many compounds, for example, N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1Product Details of 50534-23-1).

N-(1-Benzylpiperidin-4-yl)acetamide (cas: 50534-23-1) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Several piperidine alkaloids isolated from natural herbs, were found to exhibit antiproliferation and antimetastatic effects on various types of cancers both in vitro and in vivo for example Piperine, Evodiamine, Matrine, Berberine and Tetrandine.Product Details of 50534-23-1

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Abdel-Rehim, Mohamed et al. published their research in Journal of Microcolumn Separations in 2001 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Application of 27262-40-4

Determination of ropivacaine and its metabolites in human plasma using solid phase microextraction and GC-NPD / GC-MS was written by Abdel-Rehim, Mohamed;Andersson, Mikael;Portelius, Erik;Norsten-Hoog, Carina;Blomberg, Lars G.. And the article was included in Journal of Microcolumn Separations in 2001.Application of 27262-40-4 This article mentions the following:

The performance of solid-phase microextraction (SPME) in combination with capillary gas chromatog. (CGC) to quantify ropivacaine and its metabolites in human plasma was studied. The anal. was performed using either a N P detector (NPD) or a mass-spectrometric detector. For extraction, Carbowax / divinylbenzene, polyacrylate and polydimethylsiloxane fibers were tested. Absorption and desorption times were studied for all analytes sep. The Carbowax / divinylbenzene fiber gave the highest recovery in plasma samples as compared to the other fibers. The effects of temperature, addition of salt, and agitation of the sample were studied. The validation of the method showed that the chromatog. selectivity was satisfactory and all metabolites were well separated SPME gave higher deviation as compared to published data for solid-phase and liquid-liquid extraction as sample preparation methods but the acceptance criteria for the study validation were well in line with the international criteria. The major disadvantage of SPME in quant. bioanal. is that the fiber does not withstand a complete run (standards + blanks + QC samples + patient samples). Also, the quality of fiber and the fiber length can differ from batch to batch. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Application of 27262-40-4).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Application of 27262-40-4

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Wolrab, Denise et al. published their research in Journal of Separation Science in 2013 | CAS: 27262-40-4

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

Click chemistry immobilization strategies in the development of strong cation exchanger chiral stationary phases for HPLC was written by Wolrab, Denise;Fruehauf, Peter;Kohout, Michal;Lindner, Wolfgang. And the article was included in Journal of Separation Science in 2013.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide This article mentions the following:

Enantioseparation of chiral amines with HPLC has developed into a widely used anal. and preparative tool. Chiral basic mols., which act as cationic species upon protonation, are suited for an enantioselective cation exchange process. Novel strong cation exchangers (SCX) based on different 3,5-disubstituted benzoic acids functionalized with trans-(R,R)- and trans-(S,S)-2-aminocyclohexanesulfonic acid as the chiral selector (SO) and ion exchange unit were synthesized. Employing 1,3-dipolar cycloaddition (azide-yne click chem.), the SOs were immobilized onto azidopropyl-modified silica gel. This immobilization strategy enables controlled loading of the SO, and especially, high SO d. on the silica surface compared to the thiol-ene click immobilization. The performance of the novel SCX chiral stationary phases was evaluated under polar organic mode conditions with different ratios of methanol and acetonitrile, thereby changing the polarity of the bulk mobile phase. The type of co- and counterion additives employed in the mobile phase was varied as well. The influence of the formed 1,2,3-triazol spacer as well as different substitution patterns in the benzene unit on the chiral recognition properties of the SOs is discussed. In the experiment, the researchers used many compounds, for example, (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide).

(S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide (cas: 27262-40-4) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Some chemotherapeutic agents have piperidine moiety within their structure, foremost among them, vinblastine and raloxifene.Name: (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem