Tag: 219.2796

Seo, Hyowon et al. published their research in Nature Chemistry in 2017 | CAS: 21319-53-9

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Synthetic Route of C13H17NO2

Photoredox activation of carbon dioxide for amino acid synthesis in continuous flow was written by Seo, Hyowon;Katcher, Matthew H.;Jamison, Timothy F.. And the article was included in Nature Chemistry in 2017.Synthetic Route of C13H17NO2 This article mentions the following:

Although carbon dioxide (CO2) is highly abundant, its low reactivity has limited its use in chem. synthesis. In particular, methods for carbon-carbon bond formation generally rely on two-electron mechanisms for CO2 activation and require highly activated reaction partners. Alternatively, radical pathways accessed via photoredox catalysis could provide new reactivity under milder conditions. Here we demonstrate the direct coupling of CO2 and amines via the single-electron reduction of CO2 for the photoredox-catalyzed continuous flow synthesis of 伪-amino acids. By leveraging the advantages of utilizing gases and photochem. in flow, a com. available organic photoredox catalyst effects the selective 伪-carboxylation of amines that bear various functional groups and heterocycles. The preliminary mechanistic studies support CO2 activation and carbon-carbon bond formation via single-electron pathways, and we expect that this strategy will inspire new perspectives on using this feedstock chem. in organic synthesis. In the experiment, the researchers used many compounds, for example, 1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9Synthetic Route of C13H17NO2).

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a saturated organic heteromonocyclic parent, an azacycloalkane, a secondary amine and a member of piperidines. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Synthetic Route of C13H17NO2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Adomenas, P. et al. published their research in Molecular Crystals and Liquid Crystals in 1985 | CAS: 97096-92-9

4-(4-Methylpiperidin-1-yl)benzoic acid (cas: 97096-92-9) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Product Details of 97096-92-9

Mesogenic esters of the 4-(alkylpiperidino) benzoic acids was written by Adomenas, P.;Sirutkaitis, R.. And the article was included in Molecular Crystals and Liquid Crystals in 1985.Product Details of 97096-92-9 This article mentions the following:

A number of 4-(4-alkylpiperidino)benzoic acids, alkyl 4-(4-alkylpiperidino)benzoates, and aryl 4-(4-alkylpiperidino)benzoates were prepared and their properties were examined (especially liquid crystal properties). In the experiment, the researchers used many compounds, for example, 4-(4-Methylpiperidin-1-yl)benzoic acid (cas: 97096-92-9Product Details of 97096-92-9).

4-(4-Methylpiperidin-1-yl)benzoic acid (cas: 97096-92-9) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Product Details of 97096-92-9

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Zhao, Ruonan et al. published their research in Catalysis Letters | CAS: 21319-53-9

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Recyclable Copper-Catalyzed Decarboxylative C-C Coupling of the sp3-Hybridized Carbon Atoms of 伪-Amino Acids was written by Zhao, Ruonan;Li, Jianying;Huang, Bin;Cai, Mingzhong. And the article was included in Catalysis Letters.Computed Properties of C13H17NO2 This article mentions the following:

A highly efficient heterogeneous copper(I)-catalyzed decarboxylative C-C coupling of 伪-amino acids with various carbon nucleophiles has been developed that proceeds smoothly in toluene at 110 掳C by using an 2-aminoethylamino-modified SBA-15-supported copper(I) bromide complex as the catalyst and di-tert-Bu peroxide as the oxidant and provides a novel and practical approach for the synthesis of diverse propargylamines ArCH2N(R1)CH(R2)C=CR3 [Ar = Ph, 4-MeC6H4, 4-FC6H4, etc., R1R2 = CH2CH2CH2, CH2(CH2)2CH2, R3 = n-hexyl, Ph, 2-thienyl, etc.], (PhCH2)2NCH2C顚咰Ph, and ArCH2N(R1)CH(R2)X [Ar = Ph, 4-MeC6H4, 4-ClC6H4, X = CH2NO2, 3-indolyl, 5-chloro-2-indolyl, etc.] in good yields. The new heterogeneous copper(I) catalyst can be facilely prepared from com. easily available and inexpensive reagents via a simple procedure and exhibits a slightly higher catalytic activity than homogeneous CuBr/TMEDA system and can be recycled at least 8 times without any apparent loss of catalytic efficiency. In the experiment, the researchers used many compounds, for example, 1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9Computed Properties of C13H17NO2).

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Zhao, Ruonan et al. published their research in Catalysis Letters | CAS: 21319-53-9

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Recyclable Copper-Catalyzed Decarboxylative C-C Coupling of the sp3-Hybridized Carbon Atoms of α-Amino Acids was written by Zhao, Ruonan;Li, Jianying;Huang, Bin;Cai, Mingzhong. And the article was included in Catalysis Letters.Computed Properties of C13H17NO2 This article mentions the following:

A highly efficient heterogeneous copper(I)-catalyzed decarboxylative C-C coupling of α-amino acids with various carbon nucleophiles has been developed that proceeds smoothly in toluene at 110 °C by using an 2-aminoethylamino-modified SBA-15-supported copper(I) bromide complex as the catalyst and di-tert-Bu peroxide as the oxidant and provides a novel and practical approach for the synthesis of diverse propargylamines ArCH2N(R1)CH(R2)C=CR3 [Ar = Ph, 4-MeC6H4, 4-FC6H4, etc., R1R2 = CH2CH2CH2, CH2(CH2)2CH2, R3 = n-hexyl, Ph, 2-thienyl, etc.], (PhCH2)2NCH2CCPh, and ArCH2N(R1)CH(R2)X [Ar = Ph, 4-MeC6H4, 4-ClC6H4, X = CH2NO2, 3-indolyl, 5-chloro-2-indolyl, etc.] in good yields. The new heterogeneous copper(I) catalyst can be facilely prepared from com. easily available and inexpensive reagents via a simple procedure and exhibits a slightly higher catalytic activity than homogeneous CuBr/TMEDA system and can be recycled at least 8 times without any apparent loss of catalytic efficiency. In the experiment, the researchers used many compounds, for example, 1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9Computed Properties of C13H17NO2).

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem

 

Zhao, Ruonan et al. published their research in Catalysis Letters | CAS: 21319-53-9

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Recyclable Copper-Catalyzed Decarboxylative C-C Coupling of the sp3-Hybridized Carbon Atoms of α-Amino Acids was written by Zhao, Ruonan;Li, Jianying;Huang, Bin;Cai, Mingzhong. And the article was included in Catalysis Letters.Computed Properties of C13H17NO2 This article mentions the following:

A highly efficient heterogeneous copper(I)-catalyzed decarboxylative C-C coupling of α-amino acids with various carbon nucleophiles has been developed that proceeds smoothly in toluene at 110 °C by using an 2-aminoethylamino-modified SBA-15-supported copper(I) bromide complex as the catalyst and di-tert-Bu peroxide as the oxidant and provides a novel and practical approach for the synthesis of diverse propargylamines ArCH2N(R1)CH(R2)C=CR3 [Ar = Ph, 4-MeC6H4, 4-FC6H4, etc., R1R2 = CH2CH2CH2, CH2(CH2)2CH2, R3 = n-hexyl, Ph, 2-thienyl, etc.], (PhCH2)2NCH2CCPh, and ArCH2N(R1)CH(R2)X [Ar = Ph, 4-MeC6H4, 4-ClC6H4, X = CH2NO2, 3-indolyl, 5-chloro-2-indolyl, etc.] in good yields. The new heterogeneous copper(I) catalyst can be facilely prepared from com. easily available and inexpensive reagents via a simple procedure and exhibits a slightly higher catalytic activity than homogeneous CuBr/TMEDA system and can be recycled at least 8 times without any apparent loss of catalytic efficiency. In the experiment, the researchers used many compounds, for example, 1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9Computed Properties of C13H17NO2).

1-Benzylpiperidine-2-carboxylic acid (cas: 21319-53-9) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Computed Properties of C13H17NO2

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem