With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.167757-45-1,Benzyl 4-(aminocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate,as a common compound, the synthetic route is as follows.,167757-45-1
General procedure: To a solution of the aldoxime or the amide (1.0 mmol) and Et3N (1.5mmol) in EtOAc (1 mL, 1 M) at r.t. was added XtalFluor-E8 (1.1 mmol)portionwise over ca. 2 min. The resulting solution was stirred at r.t.for 1 h. The reaction mixture was quenched with sat. aq Na2CO3 and extracted with CH2Cl2 (2 ¡Á 10 mL). The combined organic layers were washed with H2O and brine, dried (MgSO4), and concentrated under vacuum to afford the crude nitrile, which was purified by flash chromatography, if required.
167757-45-1 Benzyl 4-(aminocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate 2776131, apiperidines compound, is more and more widely used in various.
Reference£º
Article; Keita, Massaba; Vandamme, Mathilde; Paquin, Jean-Francois; Synthesis; vol. 47; 23; (2015); p. 3758 – 3766;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem