Anonymous et al. published their research in Federal Register in 1964 | CAS: 142-64-3

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine is a fairly basic compound and is an amine solvent. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Recommanded Product: 142-64-3

March 1964 and corrections was written by Anonymous. And the article was included in Federal Register in 1964.Recommanded Product: 142-64-3 This article mentions the following:

The following new drugs have been approved for human use: ethynylestradiol and norethindrone acetate; aspirin, phenacetin, caffeine and orphenadrine citrate; norethindrone and mestranol; lidocaine, Bi subgallate, ZnO, Al subacetate, and Peruvian balsam; nalidixic acid; lidocaine; pralidoxime chloride; ammonium form of cross-linked polyacrylic (carboxylic) cation-exchange resin; and for veterinary use: trichlorfon, phenothiazine, and piperazine-di-HCl. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Recommanded Product: 142-64-3).

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine is a fairly basic compound and is an amine solvent. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid).Recommanded Product: 142-64-3

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics

 

Hammouda, M. et al. published their research in Pharmazie in 1988 | CAS: 142-64-3

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Synthetic Route of C4H12Cl2N2

Synthesis and some reactions of 2-(3-aminopropionyl)-1,3-indandiones was written by Hammouda, M.;Hamama, W. S.;Kandeel, E. M.;Afsah, E. M.. And the article was included in Pharmazie in 1988.Synthetic Route of C4H12Cl2N2 This article mentions the following:

The title compounds I (R2N = 1,4-piperazinediyl, Me2N, morpholino) were prepared by Mannich reaction of 2-acetyl-1,3-indandione (II) with R2NH and CH2O. Reactions of I with PhNH2, glycine, piperazine, PhNHNH2, and HONH2 were investigated. Thus, I (R2N = morpholino) and PhNHNH2 gave the indenopyrazole III. II and HSCH2CO2H gave the thiazolidine IV. In the experiment, the researchers used many compounds, for example, Piperazine Dihydrochloride (cas: 142-64-3Synthetic Route of C4H12Cl2N2).

Piperazine Dihydrochloride (cas: 142-64-3) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.Synthetic Route of C4H12Cl2N2

Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics