142752-12-3, 1-(4-Aminophenyl)piperidin-4-ol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 23 7-[4-(4-Hydroxypiperidin-1-yl)phenylamino]-1-isopropyl-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2(1H)-one Prepared from 200 mg (0.79 mmol) of 1-isopropyl-7-methanesulfinyl-3,4-dihydro-pyrimido[4,5-d]pyrimidin-2(1H)-one, 302 mg (1.57 mmol) of 1-(4-aminophenyl)-4-hydroxypiperidine and 182 muL (2.36 mmol) of trifluoroacetic acid in 3.2 mL of acetonitrile. After the workup, the crude residue is triturated in ethyl acetate/dichloromethane and filtered. The filtrate is concentrated further to produce a second crop of crystals. The two are combined and dried to give 45 mg (13%) of the title compound: mp >120 C. (dec). Analysis calculated for C20H26N6O2.0.3 C4H8O2.0.5 H2O: C, 60.93; H, 7.09; N, 20.11. Found: C, 60.95; H, 6.82; N, 20.35.
The synthetic route of 142752-12-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Dobrusin, Ellen Myra; Hamby, James Marino; Kramer, James Bernard; Schroeder, Mel Conrad; Showalter, Howard Daniel Hollis; Toogood, Peter; Trumpp-Kallmeyer, Susanne A.; US2004/44012; (2004); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem