Szczepanska, Elzbieta published the artcileEfficient method for the concentration determination of Fmoc groups incorporated in the core-shell materials by Fmoc-glycine, Computed Properties of 35661-58-6, the publication is Molecules (2020), 25(17), 3983, database is CAplus and MEDLINE.
In this paper, we described the synthesis procedure of TiO2@SiO2 core-shell modified with 3-(aminopropyl)trimethoxysilane (APTMS). The chem. attachment of Fmoc-glycine (Fmoc-Gly-OH) at the surface of the core-shell structure was performed to determine the amount of active amino groups on the basis of the amount of Fmoc group calculation We characterized nanostructures using various methods: transmission electron microscope (TEM), SEM (SEM), Fourier-transform IR spectroscopy (FTIR), thermogravimetric anal. (TGA) and XPS to confirm the modification effectiveness. The UV-visible spectroscopy (UV-vis) measurement was adopted for the quant. determination of amino groups present on the TiO2@SiO2 core-shell surface by determination of Fmoc substitution. The nanomaterials were functionalized by Fmoc-Gly-OH and then the fluorenylmethyloxycarbonyl (Fmoc) group was cleaved using 20% (ν/ν) solution of piperidine in DMF. This reaction led to the formation of a dibenzofulvene-piperidine adduct enabling the estimation of free Fmoc groups by measurement the maximum absorption at 289 and 301 nm using UV-vis spectroscopy. The calculations of Fmoc loading on core-shell materials was performed using different molar absorption coefficient: 5800 and 6089 dm3 x mol-1 x cm-1 for λ = 289 nm and both 7800 and 8021 dm3 x mol-1 x cm-1 for λ = 301 nm. The obtained results indicate that amount of Fmoc groups present on TiO2@SiO2-(CH2)3-NH2 was calculated at 6 to 9μmol/g. Furthermore, all measurements were compared with Fmoc-Gly-OH used as the model sample.
Molecules published new progress about 35661-58-6. 35661-58-6 belongs to piperidines, auxiliary class Piperidine,Benzene, name is 1-((9H-Fluoren-9-yl)methyl)piperidine, and the molecular formula is C7H13NO2, Computed Properties of 35661-58-6.
Referemce:
https://en.wikipedia.org/wiki/Piperidine,
Piperidine | C5H11N – PubChem