Stefanachi, Angela et al. published their research in Bioorganic & Medicinal Chemistry in 2008 | CAS: 58333-75-8

4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Synthetic Route of C12H17NO

1-, 3- And 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor. [Erratum to document cited in CA149:000438] was written by Stefanachi, Angela;Brea, Jose Manuel;Cadavid, Maria Isabel;Centeno, Nuria B.;Esteve, Cristina;Loza, Maria Isabel;Martinez, Ana;Nieto, Rosa;Ravina, Enrique;Sanz, Ferran;Segarra, Victor;Sotelo, Eddy;Vidal, Bernat;Carotti, Angelo. And the article was included in Bioorganic & Medicinal Chemistry in 2008.Synthetic Route of C12H17NO This article mentions the following:

In Tables 1 (pages 2855-2858), 2 (page 2859-2860), and 3 (page 2861), the second column heading, “R1/R3“, was incorrectly given, and should read: “R3/R1“. On page 2858, in Table 2, for compound 58, in the second column, “(CH3)2CHCH2/Pr”, was incorrectly given, and should read “CH3/(CH3)2CHCH2“. On page 2861, in Table 3, for compound 87, in the second column, “CH3/Pr” was incorrectly given, and should read “Pr/CH3“. In the experiment, the researchers used many compounds, for example, 4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8Synthetic Route of C12H17NO).

4-(2-Methoxyphenyl)piperidine (cas: 58333-75-8) belongs to piperidine derivatives. The piperidine ring can be found not only in more than half of the currently known structures of alkaloids, but also in many natural or synthetic compounds with interesting biological activities. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Synthetic Route of C12H17NO

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem