Song, Jin Woo published the artcileSynthesis of Carbamoyl Fluorides via a Selective Fluorinative Beckmann Fragmentation, Recommanded Product: tert-Butyl piperidin-4-ylcarbamate, the main research area is carbamoyl fluoride preparation; oximinoamide fluorinative Beckmann fragmentation.
A fluorinative Beckmann fragmentation of α-oximinoamides RC(O)C(CH3)=NOH [R = bis(cyclohexylmethyl)aminyl, piperidin-1-yl, morpholin-4-yl, etc.], I (n = 0, 1, 2) and II (R1 = Me, Ph, [5-(trifluoromethyl)furan-2-yl]methyl, etc.) was devised to provide synthetically useful carbamoyl fluorides RC(O)F, C6H5CH2N(CH2(CH2)nCH2CN)C(O)F and 2-CN-C6H4-N(R1)C(O)F. High selectivity for fragmentation over a potentially competing Beckmann rearrangement was observed This protocol has a distinct mechanism and it is a different substrate scope compared with other synthetic methods. The α-oximinoamides derived from the readily available secondary amines such as piperidine, morpholine, isoindoline, etc. lactams III, or isatins IV were converted into structurally diverse carbamoyl fluorides.
Organic Letters published new progress about Beckmann rearrangement. 73874-95-0 belongs to class piperidines, name is tert-Butyl piperidin-4-ylcarbamate, and the molecular formula is C10H20N2O2, Recommanded Product: tert-Butyl piperidin-4-ylcarbamate.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem