76444-51-4, 4-Bromo-1-methylpiperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Taking 5-iodospiro[chroman-2,4′-piperidine]hydrochloride 10.0 mmol,Dissolved in 150ml of ethanol, adding 2N aqueous solution of cesium carbonate 20ml,Then add 10.0 mmol of 4-bromo-1-methylpiperidine dissolved in 50 ml of ethanol.The solution is stirred under reflux, and TCL monitors the progress of the reaction.After 5 hours, the reaction was completed; the solvent was evaporated to dryness under reduced pressure.Diluted with water and extracted with chloroform. The organic layer was dried, then evaporated. Separated 5-iodo-1′-(1-methyl-piperidin-4-yl)spiro[chroman-2,4′-piperidine]3.77 g, yield 88.4%.
76444-51-4 4-Bromo-1-methylpiperidine 11521361, apiperidines compound, is more and more widely used in various.
Reference£º
Patent; Mudanjiang Medical School; Dong Libin; Zhang Juan; Zhang Yu; Lin Shishan; Gao Chunmei; Wang Tongtong; (15 pag.)CN108752360; (2018); A;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem