With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.73874-95-0,tert-Butyl piperidin-4-ylcarbamate,as a common compound, the synthetic route is as follows.
Step 1: To a solution of tert-butyl piperidin-4-ylcarbamate (10 g, 50 mmol) and TEA (10 mL, 775 mmol) in DCM (50 mL) was added acetic anhydride (5.1 g, 50 mmol) at 0C. The resulting mixture was stirred at 0C for 1.5 h. The reaction was quenched with water (30 mL), and the organic layer was washed with saturated aqueous sodium bicarbonate (50 mL), dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford tert-butyl (1-acetylpiperidin-4-yl)carbamate as a solid, which was used in next step without further purification., 73874-95-0
As the paragraph descriping shows that 73874-95-0 is playing an increasingly important role.
Reference£º
Patent; CTxT PTY LIMITED; BERGMAN, Ylva Elisabet; CAMERINO, Michelle Ang; WALKER, Scott Raymond; STUPPLE, Paul Anthony; (135 pag.)WO2017/153513; (2017); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem