With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.72551-53-2,Ethyl 1-benzylpiperidine-3-carboxylate,as a common compound, the synthetic route is as follows.
72551-53-2, General procedure: Each ethyl N-substituted nipecotate derivative/ethyl N-substitutedisonipecotate derivative (1 mol) in 30 mL ethanol and hydraziniumhydroxide (10 mol) were heated under microwave irradiation (130 C,300 W) or refluxed for 24-48 h in an oil bath. After completion of thereaction (TLC), ethanol was evaporated and the residue was extractedwith dichloromethane or diethyl ether. The solvent was evaporatedunder reduced pressure until an oily residue occured. Then n-hexanewas added to the residue to give the title compound as a white solid.The precipitated crystals were separated by filtration.
As the paragraph descriping shows that 72551-53-2 is playing an increasingly important role.
Reference：
Article; Parlar, Sulunay; Sayar, Gozde; Tarikogullari, Ayse Hande; Karadagli, Sumru Sozer; Alptuzun, Vildan; Erciyas, Ercin; Holzgrabe, Ulrike; Bioorganic Chemistry; vol. 87; (2019); p. 888 – 900;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem